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The Technion Israel Institute of Technology (Hebrew: ) is an institute of technology in Haifa, Israel. Originally called the Technikum, it was founded in 1912. The emphasis was on natural sciences, engineering and architecture, with a school of medicine added later. The Technion is home to Israel's first Nobel laureates in science, Avram Hershko and Aaron Ciechanover who won the 2004 Nobel Prize in Chemistry for discovering the ubiquitin system the mechanism responsible for disassembling protein in the cell.