Andere Kunden interessierten sich auch für
![Science of New Paradigm]( "Science of New Paradigm")
Science of New Paradigm13,99 €![The Expression Of P53 Gene In Colorectal carcinoma By Real - Time PCR]( "The Expression Of P53 Gene In Colorectal carcinoma By Real - Time PCR")
The Expression Of P53 Gene In Colorectal carcinoma By Real - Time PCR46,99 €![Mutational Analysis of p53 gene and dietary risk factors]( "Mutational Analysis of p53 gene and dietary risk factors")
Mutational Analysis of p53 gene and dietary risk factors23,99 €![Challenges In Isolation Of Full Length Vacuolating Cytotoxin VacA]( "Challenges In Isolation Of Full Length Vacuolating Cytotoxin VacA")
Challenges In Isolation Of Full Length Vacuolating Cytotoxin VacA23,99 €![Oxidative Damage to Nucleic Acids]( "Oxidative Damage to Nucleic Acids")
Oxidative Damage to Nucleic Acids110,99 €![Effect of plate length and surface roughness on the flow and aeroacoustic characteristics of wall jets]( "Effect of plate length and surface roughness on the flow and aeroacoustic characteristics of wall jets")
Effect of plate length and surface roughness on the flow and aeroacoustic characteristics of wall jets26,99 €![Chromatin Protocols]( "Chromatin Protocols")
Chromatin Protocols74,99 €
Gliomas are the most common primary brain tumors and have a poor prognosis. Traditionally they were managed with resection and radiotherapy but chemotherapy is assuming an increasingly important role. Only a small sub-set of patients benefit from chemotherapy however, due to the multidrug resistance phenomenon. Tumors may have an endogenous drug resistance, or may develop resistance to previously effective therapeutic agents to which they have been exposed. It has been proposed that the ATP-dependent drug efflux channel, P-glycoprotein (P-gP), Survivin, Telomere and the mutation in P53 protein; affect chemoresistance in cancer cells. Moreover, traditional method for subgrouping patients into various prognostic groups by histomorphologic grading has been subjective and unreliable in predicting the prognosis of individual patients. Thus, there is a need for more sophisticated prognostic determinants.