This textbook provides a system based approach to Medical Microbiology; comprising 100 chapters included bacteriology, virology, mycology, parasitology and immunology. The book provides all essential information regarding the general characters of microorganisms i.e., morphology, antigenic structure, pathogenesis, clinical manifestations, method of specimen collection, microscopic examination, culture, identification of microorganism, treatment, prevention and control. Regarding examination point of view each chapter have been provided with questions such as long answer questions, short answer questions and multiple choice questions. It will help students to overcome their nervousness and stress in examination period and built self confidence. This book has been written in simple language, easily understandable, need based; well labeled diagram and tables have been furnished at appropriate places. This textbook would be useful for the students of medical, dental, nursing and paramedical sciences of graduate and postgraduate levels. It is also hoped that it will serve as a resource for teachers of microbiology and medical professionals.