Pharmacologic behavior management introduces a new level of risk, which can be managed by appropriately trained providers paying careful attention to preoperative assessment, emergency preparedness, intraoperative monitoring, and post-operative evaluation.In light of new approaches to risk assessment, changing disease patterns, and the emphasis on nonsurgical management in pediatric dentistry, the amount of information influencing clinical decisions is greater than ever. This book will attempt to categorize the variables and pose a framework to navigate clinical decision-making at the intersection of behavior and disease management in pediatric dentistry.