The Autoimmune Diseases

Herausgeber: Gershwin, M Eric; Tsokos, George C

• Gebundenes Buch

Produktbeschreibung

Gives a thorough and important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and its therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant Includes new, updated chapters that emphasize hot topics in the field, e.g., research on auto inflammatory diseases and autoimmune responses following cancer immunotherapy

Produktdetails

• Verlag: Elsevier Health Sciences
• 6th edition
• Seitenzahl: 1532
• Erscheinungstermin: 11. November 2019
• Englisch
• Abmessung: 284mm x 222mm x 58mm
• Gewicht: 3247g
• ISBN-13: 9780128121023
• ISBN-10: 0128121025
• Artikelnr.: 57976972

Inhaltsangabe

Section 1: Immunologic Basis of Autoimmunity 1. Prelude: Historical
introduction to autoimmunity and autoimmune disease 2. Structural and
Functional Aspects of the Innate and Adaptive Systems of Immunity 3.
General Features of Autoimmune Diseases 4. Antigen Presentation, Dendritic
Cells, and Autoimmunity 5. T cells and their subsets 6. Role of Th1 Th2
Th17 Cells in Autoimmunity 7. Tolerance and Autoimmunity: T Cells 8.
Regulatory T Cells 9. B Cells and Autoimmunity 10. Immunological memory T
cells 11. Immunological memory B cells 12. Apoptotic Cells as a Source of
Autoantigens 13. Effector Mechanisms of Autoimmunity: Antibodies and Immune
Complexes 14. Functional Effects of Autoantibodies 15. Cytokine Chemokines
16. Signaling Pathways in T and B Lymphocytes 17. HLA Genetics and
Autoimmunity 18. Non HLA Genetics 19. AIRE related Autoimmunity 20. Immune
Deficiencies and Autoimmunity 21. Infections and Autoimmunity 22.
Noninfectious Environmental Agents and Autoimmunity 23. Sex, Pregnancy and
Autoimmunity 24. Animal Models of Autoimmune Disease
Section 2: Multisystem Diseases 25. Systemic Lupus Erythematosus 26.
Systemic Sclerosis, Scleroderma 27. Antiphospholipid Syndrome 28. Sjogren
Syndrome 29. Rheumatoid Arthritis 30. Spondyloarthritis and Chronic
Idiopathic Arthropathies 31. Myositis 32. Thyroid Disease 33. Type 1
Diabetes 34. Adrenalitis 35. Polyendocrine Syndromes 36. Gastritis and
Pernicious Anemia 37. Hypophysitis 38. Hemolytic Anemia 39.
Thrombocytopenic Purpura 40. Neutropenia 41. Aplastic Anemia 42. Clotting
Disorders 43. Multiple Sclerosis 44. Peripheral Neuropathy 45. Myasthenia
Gravis 46. Ocular Disease 47. Inner Ear Disease 48. Celiac Disease 49.
Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn's Disease 50.
Chronic Hepatitis 51. Primary Billiary Cirrhosis 52. Primary Sclerosing
Cholangitis 53. Pancreatitis 54. Bullous Skin Diseases: Pemphigus and
Pemphigoid 55. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and
Urticaria 56. Kidney Disease: Goodpasture's Disease, Lupus Nephritis,
ANCA-Associated Glomerulonephritis 57. Orchitis and Male Infertility 58.
Oophoritis 59. Rheumatic Heart Disease 60. Myocarditis and Dilated
Cardiomyopathy 61. Necrotizing Arteritis and Small Vessel Vasculitis 62.
Large and Medium Vessel Vasculitides 63. Autoimmune Disorders of the Lung
64. Paraneoplastic Diseases 65. Antibody-Associated Neurological Diseases
66. Autoinflammatory and other Related Diseases
Section 3: Diagnosis, Prevention, and Therapy 67. Autoantibody Assays,
Testing, and Standardization 68. Prediction of Autoimmune Disease 69.
Emerging Therapies for Autoimmune Diseases 70. Postlude