The purpose of this study was to conceive a new way of approaching the laboratory in Biology with a constructivist vision in General Secondary Education, therefore, the main challenge of the study was focused on reviewing the teachers' didactic conception and the way Biology is being taught in the L.N.Dr. Pedro Manuel Arcaya and Dr. Carlos Diez del Ciervo. As for the methodology, the interpretative paradigm was used, with a qualitative approach, the selected method was the phenomenological one, assuming Heidegger's postulates to understand the principles and foundations of this community of teachers. The techniques used to collect the information were in-depth interviews and participant observation, and the analysis was carried out through grounded theory, in its two dimensions, the Continuous Comparison Method (CQM) and Theoretical Sampling (TM). In addition to the structuring, contrasting, triangulation and theorization proper to qualitative research.