The Biology of Germinal Centers in Lymphoid Tissue

Herausgegeben:Thorbecke, G. Jeanette; Tsiagbe, Vincent K.

• Broschiertes Buch

Produktbeschreibung

This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.

Produktdetails

• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-662-13143-5
• Softcover reprint of the original 1st ed. 1998
• Seitenzahl: 256
• Erscheinungstermin: 22. Januar 2013
• Englisch
• Abmessung: 235mm x 155mm x 15mm
• Gewicht: 397g
• ISBN-13: 9783662131435
• ISBN-10: 3662131439
• Artikelnr.: 39195745

Inhaltsangabe

1. Overview of Germinal Center Function and Structure in Normal and Genetically Engineered Mice.- 2. The Germinal Center Reaction: Influence of FDC Function in Normal, Aged, and Retrovirus Infected Hosts.- 3. T and B Lymphocytes in Germinal Centers.- 4. Somatic Hypermutation of Immunoglobulin Genes.- 5. Germinal Center Derived Lymphomas in Humans and Mice.- Color Figures.