This piece of work provides the readers a comprehensive vision about the nature and genetics of the bitter melon. On the basis of various traits considered under investigation, significant genetic aspects viz., variability, heritability, genetic advance, correlation, path coefficient analysis, etc. have been exploited. The contents of this research oriented book will act as a helping hand for the students, scholars, researchers, and progressive farmers. This book is an exemplary amalgamation of research as well as theoretical know-how regarding the concerned crop. Although pioneer works have been done with respect to the genetics facet of the crop still a lot is yet to be explored. Hence, this is a little effort from the authors' side.