Alexandre Pratt (ed.)

The Blood-Brain Barrier and Its Microenvironment

Basic Physiology to Neurological Disease
Herausgeber: Prat, Alexandre; de Vries, Elga

• Gebundenes Buch

Produktbeschreibung

This reference analyzes the cellular and molecular biology and mechanisms of the blood-brain barrier (BBB) and presents the most recent studies on the role of the BBB in the development and initiation of a wide range of physiological and pathological conditions affecting the central nervous system.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 544
• Erscheinungstermin: 24. August 2005
• Englisch
• Abmessung: 235mm x 157mm x 34mm
• Gewicht: 931g
• ISBN-13: 9780849398926
• ISBN-10: 0849398924
• Artikelnr.: 21733209

Autorenporträt

Elga de Vries, Alexandre Prat

Inhaltsangabe

Development of the Blood-Brain Barrier. Blood-Brain Barrier Genomics and
Proteomics. Tight Junctions of the Blood-Brain Barrier. Trophic Factors and
Cerebrovascular Regulation. Neuronal Influence at the BBB and Local Control
of Microcirculation. The Transport Systems of the Blood-Brain Barrier. Drug
Delivery Through the BBB: Non Viral Vectors. Immune Functions of Brain
Endothelial Cells. T Cell Migration Across the Blood-Brain Barrier in CNS
Inflammatory Diseases. Endothelial ICAM-1 Mediated Signalling and Its Role
During Lymphocyte Migration into the CNS Parenchyma. Monocyte Migration
across the BBB. Cerebral Perivascular Macrophages and the Blood-Brain
Barrier. Chemokines at the Blood-Brain Barrier. Matrix Metalloproteinase
and Proteolytic Opening of the Blood-Brain Carrier in Neuroinflammation.
Endothelial cells, Extracellular Matrix and Astocytes: Interplay for
Managing the Blood-Brain Barrier. Molecular Modulation of the Blood-Brain
Barrier During Stroke. Apolipoprotein E, the Blood-Brain Barrier and
Alzheimer's Disease. Techniques for Measuring the Blood-Brain Barrier
Integrity. Influence of Brain Trauma on Blood-Brain Barrier Properties.
Non-HIV Viral Interaction with the BBB