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A systematic and mathematically accessible introductory text explaining cell functions through the engineering principles of robust devices.
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A systematic and mathematically accessible introductory text explaining cell functions through the engineering principles of robust devices.
Produktdetails
- Produktdetails
- Verlag: Cambridge University Press
- Seitenzahl: 436
- Erscheinungstermin: 26. März 2019
- Englisch
- Abmessung: 260mm x 208mm x 32mm
- Gewicht: 1604g
- ISBN-13: 9781107052734
- ISBN-10: 1107052734
- Artikelnr.: 48456354
- Verlag: Cambridge University Press
- Seitenzahl: 436
- Erscheinungstermin: 26. März 2019
- Englisch
- Abmessung: 260mm x 208mm x 32mm
- Gewicht: 1604g
- ISBN-13: 9781107052734
- ISBN-10: 1107052734
- Artikelnr.: 48456354
Michael Sheetz is Chair of Biological Science at Columbia University, Founding Chair of the Department of Cell Biology at Duke University, and Founding Director of the Mechanobiology Institute at the National University of Singapore. He is also a recipient of the Albert Lasker Basic Medical Research Award.
Part I. Principle of Complex Function in Robust Machines: 1. Robust
self-replicating machines shaped by evolution; 2. Complex functions of
robust machines with emergent properties; 3. Integrated complex functions
with dynamic feedback; 4. Cells exhibit multiple states, each with
different functions; 5. Life at low Reynolds number and the mesoscale leads
to stochastic phenomena; Part II. Design and Operation of Complex
Functions: 6. Engineering lipid bilayers to provide fluid boundaries and
mechanical controls; 7. Membrane trafficking - flow and barriers create
asymmetries; 8. Signaling and cell volume control through ion transport and
volume regulators; 9. Structuring a cell by cytoskeletal filaments; 10.
Moving and maintaining functional assemblies with motors; 11.
Microenvironment controls life, death and regeneration; 12. Adjusting cell
shape and forces with dynamic filament networks; 13. DNA packaging for
information retrieval and propagation; 14. Transcribing the right
information and packaging for delivery; 15. Turning RNA into functional
proteins and removing unwanted proteins; Part III. Coordination of Complex
Functions: 16. How to approach a coordinated function - cell rigidity
sensing and force generation across length scale; 17. Integration of
cellular functions for decision making; 18. Moving from omnipotency to
death; 19. Cancer versus regeneration - the wrong versus right response to
the microenvironment.
self-replicating machines shaped by evolution; 2. Complex functions of
robust machines with emergent properties; 3. Integrated complex functions
with dynamic feedback; 4. Cells exhibit multiple states, each with
different functions; 5. Life at low Reynolds number and the mesoscale leads
to stochastic phenomena; Part II. Design and Operation of Complex
Functions: 6. Engineering lipid bilayers to provide fluid boundaries and
mechanical controls; 7. Membrane trafficking - flow and barriers create
asymmetries; 8. Signaling and cell volume control through ion transport and
volume regulators; 9. Structuring a cell by cytoskeletal filaments; 10.
Moving and maintaining functional assemblies with motors; 11.
Microenvironment controls life, death and regeneration; 12. Adjusting cell
shape and forces with dynamic filament networks; 13. DNA packaging for
information retrieval and propagation; 14. Transcribing the right
information and packaging for delivery; 15. Turning RNA into functional
proteins and removing unwanted proteins; Part III. Coordination of Complex
Functions: 16. How to approach a coordinated function - cell rigidity
sensing and force generation across length scale; 17. Integration of
cellular functions for decision making; 18. Moving from omnipotency to
death; 19. Cancer versus regeneration - the wrong versus right response to
the microenvironment.
Part I. Principle of Complex Function in Robust Machines: 1. Robust
self-replicating machines shaped by evolution; 2. Complex functions of
robust machines with emergent properties; 3. Integrated complex functions
with dynamic feedback; 4. Cells exhibit multiple states, each with
different functions; 5. Life at low Reynolds number and the mesoscale leads
to stochastic phenomena; Part II. Design and Operation of Complex
Functions: 6. Engineering lipid bilayers to provide fluid boundaries and
mechanical controls; 7. Membrane trafficking - flow and barriers create
asymmetries; 8. Signaling and cell volume control through ion transport and
volume regulators; 9. Structuring a cell by cytoskeletal filaments; 10.
Moving and maintaining functional assemblies with motors; 11.
Microenvironment controls life, death and regeneration; 12. Adjusting cell
shape and forces with dynamic filament networks; 13. DNA packaging for
information retrieval and propagation; 14. Transcribing the right
information and packaging for delivery; 15. Turning RNA into functional
proteins and removing unwanted proteins; Part III. Coordination of Complex
Functions: 16. How to approach a coordinated function - cell rigidity
sensing and force generation across length scale; 17. Integration of
cellular functions for decision making; 18. Moving from omnipotency to
death; 19. Cancer versus regeneration - the wrong versus right response to
the microenvironment.
self-replicating machines shaped by evolution; 2. Complex functions of
robust machines with emergent properties; 3. Integrated complex functions
with dynamic feedback; 4. Cells exhibit multiple states, each with
different functions; 5. Life at low Reynolds number and the mesoscale leads
to stochastic phenomena; Part II. Design and Operation of Complex
Functions: 6. Engineering lipid bilayers to provide fluid boundaries and
mechanical controls; 7. Membrane trafficking - flow and barriers create
asymmetries; 8. Signaling and cell volume control through ion transport and
volume regulators; 9. Structuring a cell by cytoskeletal filaments; 10.
Moving and maintaining functional assemblies with motors; 11.
Microenvironment controls life, death and regeneration; 12. Adjusting cell
shape and forces with dynamic filament networks; 13. DNA packaging for
information retrieval and propagation; 14. Transcribing the right
information and packaging for delivery; 15. Turning RNA into functional
proteins and removing unwanted proteins; Part III. Coordination of Complex
Functions: 16. How to approach a coordinated function - cell rigidity
sensing and force generation across length scale; 17. Integration of
cellular functions for decision making; 18. Moving from omnipotency to
death; 19. Cancer versus regeneration - the wrong versus right response to
the microenvironment.