In the era of global competition, role of managers who are sent abroad for temporary assignment has become increasingly important especially for multinationals companies (MNCs). The primary role of an expatriate manager can be conceived as that of a catalyst who secures continuity of MNCs.The main objective for this study is to identify the determinants of expatriates job satisfaction in multinational corporations (MNCs). This study examines the relationship between individual-level factor, cross-cultural adjustment and family influences with expatriates job satisfaction in host country.The findings revealed that cross-cultural adjustment in host country is the important criteria for expatriates job satisfaction.