The research style employed for this study was a single case study on Owere Gold Mines Limited to access the challenges of procurement outsourcing in Ghana. Fifty (50) participants (senior members, unit heads and key staff including procurement officers and finance officers) who are engaged in procurement process and or activity at Owere Mines Limited were purposely selected for this study. The research also used descriptive statistics in the data analysis. The research findings point to three main conclusions: (1) that the main purpose or rationale for procurement outsourcing at Owere Gold Mines Limited is no other reason than to improve the focus of the company, (2) there are indeed challenges associated with procurement outsourcing. From the case company s perspective, hidden cost is the most common challenge they encounter so far as procurement outsourcing is concern, and (3) the study concluded that these challenges identified could be managed when outsourcing organizations do exercise tactfulness in the selection of outsourcing service providers with a wide skill-set and operational coverage.