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Obesity is a main public health problem. It is frequently described as disorder of irregular or extreme fat accumulation in adipose tissues. It is caused by a mixture of excessive nutrition intake, lack of bodily activity and genetic defenselessness. An insufficient cases are caused principally by genetic factor, endocrine complaints, medicines or psychological disorders. In Iraq, the occurrence of T2DM in obese persons is increasing and shows a great load on the public health and socioeconomic growth. The current study aims to measure some cytokines related to obesity including Lipocalin-2 and Adipolin in control individuals, diabetic obese individuals and diabetic non obese patients. Further; the study involved estimated serum levels of Malondialdehyde(MDA), Total Antioxidants Capacity (TAC) and Total Oxidant Status (TOS) and to find out a possible relationship between these markers and other parameters also estimated such as; BMI, FBS, and lipid profiles.