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Post Traumatic Stress Disorder (PTSD) is the diagnosis encompassing a cluster of distressing symptoms which is characterized by re-experiencing trauma, by avoidance behaviour and by hyper-arousal, symptoms which persist for more than a month after a traumatic event and may worsen over time. Conventional treatment methods using antidepressants and mood-enhancers, are plagued by numerous, documented side effects, such as cardiovascular complications, liver impairment, neuropsychological changes, suicidal tendencies and aggression. The aim of this research was to determine the efficacy of the homeopathic complex Pegasus t.r.s 200C® on the symptoms of PTSD in women. This research was done as a pre-test post-test non-equivalent group design with a double-blind placebo-control. After an analysis of all the results, it can be concluded that there was a significant reduction of the overall severity and intensity of PTSD symptoms over a six week duration. Pegasus t.r.s 200C® significantlyimproved ten specific symptoms of PTSD but it was especially effective in dealing with two important symptoms of PTSD, namely, re-experiencing symptom (flashbacks) and hyper-arousal symptom (irritability).