The Endothelium in Cardiovascular Disease
Broschiertes Buch

The Endothelium in Cardiovascular Disease

Pathophysiology, Clinical Presentation and Pharmacotherapy

Herausgegeben von Luescher, Thomas
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The endothelium is an important regulator of the cardiovascular system by releasing nitric oxide, prostacyclin, endothelin-1, and other endothelium-derived constricting factors which are able to profoundly affect vascular tone and the function of circulating blood cells such as platelets and monocytes. In addition, the endothelium is a source of factors which can activate or inhibit vascular smooth muscle cell migration and proliferation. Endothelial dysfunction, with an imbalanced production of these factors, therefore, can profoundly affect vascular tone and structure as well as the function...