Our study focuses on the determinants of early sexual debut among adolescents in Kenge, conducted for a period from April to November 2022. Adolescence is a period during which the individual is more exposed to the positive and negative influences of society, and to the temptation to experiment. Identifying the concerns of adolescents through research is one of the priorities for public health, in order to identify avenues of intervention aimed at the development of a healthy and adapted sexuality. We therefore asked ourselves the following key question: What are the determinants of early sexual debut among adolescents in the city of Kenge? Our main hypothesis was that socio-cultural, socio-economic and environmental factors would be determinants of early sexual debut among adolescents in Kenge. As our study was prospective, we used a literature review with a structured interview as a survey technique, based on a questionnaire as a tool.