COVID-19 is an acute respiratory syndrome caused by the new coronavirus; SARS-COV-2 and has so impacted all sectors of human life in my country. This infectious disease is a zoonosis, which emerged in December 2019 in the city of Wuhan, in China's Hubei province, from which Mali recorded its first two confirmed cases of the epidemic on March 25, 2020.We conducted a prospective study from April 1 to September 30, 2021, which aimed to assess the population's level of knowledge, attitude and practice towards coronavirus disease in the Point G village market. A convenience sampling technique was used to select participants, and data were analyzed using SPSS and R.The under-25 age group was represented in 51.7%. Male gender was represented in 62.73%. The level of knowledge of COVID-19 among our participants was good in 23.37%, and the level of practice of barrier gestures against COVID-19 among our participants was good in 10.76% for those with a higher level of education.