The Handbook of Medicinal Chemistry
Principles and Practice
Herausgeber: Davis, Andrew; Ward, Simon E
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The Handbook of Medicinal Chemistry
Principles and Practice
Herausgeber: Davis, Andrew; Ward, Simon E
- Gebundenes Buch
Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry has been revised and brought up to date to cover the past, present and future of the entire drug development process.
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Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry has been revised and brought up to date to cover the past, present and future of the entire drug development process.
Produktdetails
- Produktdetails
- Verlag: Royal Society of Chemistry
- Seitenzahl: 753
- Erscheinungstermin: 9. Dezember 2014
- Englisch
- Abmessung: 258mm x 200mm x 47mm
- Gewicht: 1666g
- ISBN-13: 9781849736251
- ISBN-10: 1849736251
- Artikelnr.: 41125694
- Verlag: Royal Society of Chemistry
- Seitenzahl: 753
- Erscheinungstermin: 9. Dezember 2014
- Englisch
- Abmessung: 258mm x 200mm x 47mm
- Gewicht: 1666g
- ISBN-13: 9781849736251
- ISBN-10: 1849736251
- Artikelnr.: 41125694
Andrew Davis read Chemistry at Imperial College of Science and Technology and then completed a PhD in Physical Organic Chemistry with Professor MI Page at the University of Huddersfield. He joined Fisons PLC Pharmaceuticals Division in 1988, which became part of the Swedish pharmaceutical company Astra AB in 1995. Astra merged with Zeneca PLC in 1999 to form AstraZeneca PLC. Dr Davis has spent the last 23 years in drug discovery, in line management, project and portfolio management and senior science roles. He has recently relocated to Sweden with AstraZeneca as Senior Principal Scientist and project leader in Chemistry with the Respiratory and Inflammation Innovative Medicines in Gothenburg. Simon Ward has an MA in Natural Sciences and a PhD in synthetic organic chemistry from Cambridge University. He has a wide ranging experience of drug discovery in both large and small companies (GlaxoSmithKline, Knoll Pharmaceuticals, Vernalis, Chiroscience) and specialist experience of discovering and developing drugs for central nervous system indications. He has led multidisciplinary project teams and medicinal chemistry groups from target identification, through to early clinical studies, delivering multiple clinical development candidates across indications. Simon is a Fellow of the Royal Society of Chemistry and is currently Professor of Medicinal Chemistry at the University of Sussex, UK and Director of the Translational Drug Discovery Group, which he established within the University of Sussex in 2010.
Introduction
Library design
Physicochemical properties and drug design
Computational chemistry
Structure-based drug design
Fragment based design
QSAR
Drug metabolism
Pharmacokinetics
Molecular biology
Computational biology
In vitro
In vivo
Translational science
Assays
Toxicology
Intellectual property
Modern drug design
Lead generation
Lead optimisation
Predictive toxicology
Pharmaceutical development
Process research
Project management
Clinical development
Case Study 1
Case Study 2
Case Study 3
Library design
Physicochemical properties and drug design
Computational chemistry
Structure-based drug design
Fragment based design
QSAR
Drug metabolism
Pharmacokinetics
Molecular biology
Computational biology
In vitro
In vivo
Translational science
Assays
Toxicology
Intellectual property
Modern drug design
Lead generation
Lead optimisation
Predictive toxicology
Pharmaceutical development
Process research
Project management
Clinical development
Case Study 1
Case Study 2
Case Study 3
Introduction
Library design
Physicochemical properties and drug design
Computational chemistry
Structure-based drug design
Fragment based design
QSAR
Drug metabolism
Pharmacokinetics
Molecular biology
Computational biology
In vitro
In vivo
Translational science
Assays
Toxicology
Intellectual property
Modern drug design
Lead generation
Lead optimisation
Predictive toxicology
Pharmaceutical development
Process research
Project management
Clinical development
Case Study 1
Case Study 2
Case Study 3
Library design
Physicochemical properties and drug design
Computational chemistry
Structure-based drug design
Fragment based design
QSAR
Drug metabolism
Pharmacokinetics
Molecular biology
Computational biology
In vitro
In vivo
Translational science
Assays
Toxicology
Intellectual property
Modern drug design
Lead generation
Lead optimisation
Predictive toxicology
Pharmaceutical development
Process research
Project management
Clinical development
Case Study 1
Case Study 2
Case Study 3