In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain.
In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
CONTENTS List of Figures ix Preface xi One: Daring to think differently 1 Root canal blues Neuro-immunology and immuno-psychiatry What does an inflamed mind look like? The revolution will not be televised Two: The workings of the immune system 20 Inflammation and infection Fig 1. Immune cells Fig 2. Inflammation Location, location, location Communication: the medium is the message Fig 3. The immune system Rapid rebuttal and learning Auto-immunity: the flip side Three: Hiding in plain sight 43 It's depressing being ill The cogito, God, and the machine Fig 4. A lady trying to explain the pineal theory of the human mind and body A long shadow Mrs P is not alone A bona fide blockbuster The Cartesian blind spot Four: Melancholia after Descartes 69 From black bile to MDD A cross to bear Super-shrink Fig 5. Freud's first draft of the ego Dancing in the sanatorium Fig 6. First prophet of pharmaceuticals The golden age Fig 7. Scenes of joy at the dawn of anti-depressants Fig 8. The seer and the synapse Farcical serotonin Bereft of biomarkers Five: How? 112 Extraordinary claims demand extraordinary evidence A stubborn fact Causes must come first The Berlin wall in the brain Fig 9. What I was taught at medical school - and what we now know Fig 10. Nervous reflex control of inflammation Inflamed brains Six: Why? 146 What could make you inflamed (and depressed)? Flaming stressed Causal chains and cycles Ultimately, the answer must always be Darwin Fig 11. Emotional faces and emotional brains A savannah survival story Seven: So what? 176 Medical apartheid Fig 12. The vicious cycle of stress, inflammation and depression - and ways to break it - an artist's impression Could it be different already? Market failure Beyond blockbusters: better but not bigger than Prozac Alzheimer's disease and the yin and yang of microglia Schizophrenia and auto-intoxication References 221 Acknowledgements 229 Disclaimers 230 Index 231
CONTENTS List of Figures ix Preface xi One: Daring to think differently 1 Root canal blues Neuro-immunology and immuno-psychiatry What does an inflamed mind look like? The revolution will not be televised Two: The workings of the immune system 20 Inflammation and infection Fig 1. Immune cells Fig 2. Inflammation Location, location, location Communication: the medium is the message Fig 3. The immune system Rapid rebuttal and learning Auto-immunity: the flip side Three: Hiding in plain sight 43 It's depressing being ill The cogito, God, and the machine Fig 4. A lady trying to explain the pineal theory of the human mind and body A long shadow Mrs P is not alone A bona fide blockbuster The Cartesian blind spot Four: Melancholia after Descartes 69 From black bile to MDD A cross to bear Super-shrink Fig 5. Freud's first draft of the ego Dancing in the sanatorium Fig 6. First prophet of pharmaceuticals The golden age Fig 7. Scenes of joy at the dawn of anti-depressants Fig 8. The seer and the synapse Farcical serotonin Bereft of biomarkers Five: How? 112 Extraordinary claims demand extraordinary evidence A stubborn fact Causes must come first The Berlin wall in the brain Fig 9. What I was taught at medical school - and what we now know Fig 10. Nervous reflex control of inflammation Inflamed brains Six: Why? 146 What could make you inflamed (and depressed)? Flaming stressed Causal chains and cycles Ultimately, the answer must always be Darwin Fig 11. Emotional faces and emotional brains A savannah survival story Seven: So what? 176 Medical apartheid Fig 12. The vicious cycle of stress, inflammation and depression - and ways to break it - an artist's impression Could it be different already? Market failure Beyond blockbusters: better but not bigger than Prozac Alzheimer's disease and the yin and yang of microglia Schizophrenia and auto-intoxication References 221 Acknowledgements 229 Disclaimers 230 Index 231
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'Suddenly an expert who wants to stop and question everything we thought we knew... This is a lesson in the workings of the brain far too important to ignore.' Jeremy Vine, BBC
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