Andere Kunden interessierten sich auch für
![Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2]( "Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2")
Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2155,99 €![NRF2 as a Central Point in Cancer Metastasis]( "NRF2 as a Central Point in Cancer Metastasis")
NRF2 as a Central Point in Cancer Metastasis27,99 €![Computational determination of novel biomarkers of colon cancer]( "Computational determination of novel biomarkers of colon cancer")
Computational determination of novel biomarkers of colon cancer25,99 €![Cancer Cell Signaling & Small Molecule Inhibitors]( "Cancer Cell Signaling & Small Molecule Inhibitors")
Cancer Cell Signaling & Small Molecule Inhibitors47,99 €![Outwitting the Dilemma of Scale]( "Outwitting the Dilemma of Scale")
Outwitting the Dilemma of Scale53,99 €![Modeling the Structure and Transition Kinetics of Small Proteins:]( "Modeling the Structure and Transition Kinetics of Small Proteins:")
Modeling the Structure and Transition Kinetics of Small Proteins:46,99 €![The Dynamic of Glucose-Insulin Endocrine Metabolic Regulatory System]( "The Dynamic of Glucose-Insulin Endocrine Metabolic Regulatory System")
The Dynamic of Glucose-Insulin Endocrine Metabolic Regulatory System40,99 €
Ndrg-1 has been found to function as a metastasis
suppressor in prostate, pancreatic, breast and other
cancers. However, the molecular function of this
elusive protein remains unknown. The aim of this
study was to examine the function of Ndrg-1 in
different cancer cells including prostate, lung and
colon cancer. These studies reveal, for the first
time, novel Ndrg-1 gene targets including Ccl2,
Hod3, Thtpa, Fmo3 and VEGF. Ndrg-1 was also found to
affect prostate cancer cell adhesion and
proliferation. Furthermore, the ability of novel
anti-cancer agents, the iron chelators, to up-
regulate Ndrg-1 was also explored. Our results
indicate that iron chelators are a promising new
treatment strategy for cancer, partly due to their
ability to increase cellular levels of this
important metastasis suppressor protein.
suppressor in prostate, pancreatic, breast and other
cancers. However, the molecular function of this
elusive protein remains unknown. The aim of this
study was to examine the function of Ndrg-1 in
different cancer cells including prostate, lung and
colon cancer. These studies reveal, for the first
time, novel Ndrg-1 gene targets including Ccl2,
Hod3, Thtpa, Fmo3 and VEGF. Ndrg-1 was also found to
affect prostate cancer cell adhesion and
proliferation. Furthermore, the ability of novel
anti-cancer agents, the iron chelators, to up-
regulate Ndrg-1 was also explored. Our results
indicate that iron chelators are a promising new
treatment strategy for cancer, partly due to their
ability to increase cellular levels of this
important metastasis suppressor protein.