The Microtubule Cytoskeleton

Organisation, Function and Role in Disease
Herausgegeben:Lüders, Jens

• Broschiertes Buch

Produktbeschreibung

This book provides an overview on the organization andfunction of the microtubule cytoskeleton, which is essential to many cellularprocesses and profoundly linked to a range of human diseases.Covering basic concepts as well as molecular details, the book discusses howmicrotubules are nucleated and organized into ordered arrays, at different cellcycle stages and in distinct cell types. In addition, the book highlights howdefects in the microtubule cytoskeleton are linked to diseases such asneurodevelopmental disorders.

The book is intended for students, graduates and moresenior researchers in cell and developmental biology as well as for medicaldoctors.

Produktdetails

• Verlag: Springer / Springer Vienna / Springer, Wien
• Artikelnr. des Verlages: 978-3-7091-1901-3
• 1st ed. 2016
• Seitenzahl: 200
• Erscheinungstermin: 19. April 2016
• Englisch
• Abmessung: 235mm x 155mm x 11mm
• Gewicht: 349g
• ISBN-13: 9783709119013
• ISBN-10: 3709119014
• Artikelnr.: 44431272

Autorenporträt

Jens Lüders, PhD, is leading the Microtubule organization group at the Institute for Research in Biomedicine (IRB), in Barcelona, Spain. 

Inhaltsangabe

Part 1. Organization of the microtubule cytoskeleton Microtubule nucleators.- Microtubule regulators.- Microtubule organizing centers. Part 2. Assembly, maintenance and function of microtubule-based organellesCentrioles/basal bodies.- Centrosomes.- Cilia. Part 3. The microtubule cytoskeleton and disease Microtubule-based.- Centrosome-based.- Ciliopathies.