This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with…mehr
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Artikelnr. des Verlages: 11998761, 978-1-934115-18-3
2nd ed.
Seitenzahl: 896
Erscheinungstermin: 13. November 2016
Englisch
Abmessung: 285mm x 215mm x 50mm
Gewicht: 2630g
ISBN-13: 9781934115183
ISBN-10: 1934115185
Artikelnr.: 27581705
Herstellerkennzeichnung
Books on Demand GmbH
In de Tarpen 42
22848 Norderstedt
info@bod.de
040 53433511
Autorenporträt
William B. Coleman Department of Pathology and Laboratory medicine, Curriculum in Toxicology, Program in Translational Medicine, UNC Lineberger Comprehensive Center, University of North Carolina School of Medicine, Chapel Hill, NC
Inhaltsangabe
Cancer Epidemiology: Incidence and Etiology of Human Neoplasms.- Essential Concepts and Techniques in Molecular Biology.- Cancer Genomics.- Cancer Cytogenetics.- The Epigenetic Basis of Human Cancer.- Cancer Proteomics.- An Overview of Cancer Genes.- Oncogenes and the Initiation and Maintenance of Tumorigenesis.- Positive Mediators of Cell Proliferation in Neoplasia: Growth Factors and Receptors.- Senescence, Apoptosis, and Cancer.- Novel Cancer Therapies Targeting Angiogenesis.- Beyond the Primary Tumor: Progression, Invasion, and Metastasis.- Simple Sequence Mutations.- Single Nucleotide Polymorphisms and Cancer Susceptibility.- Chromosomes and Chromosomal Instability in Human Cancer.- Epigenetic Mechanisms in Cancer Development.- MicroRNAs and Cancer.- Erionite and Asbestos in the Pathogenesis of Human Malignant Mesotheliomas.- Viral Mechanisms in Human Carcinogenesis.- Hormonal Carcinogenesis: The Role of Estrogens.- Sporadic Cancers.- Hereditary Cancer.- Retinoblastoma: Clinical and Molecular Perspectives.- Xeroderma Pigmentosum and the DNA Damage Response to Ultraviolet Light.- Hereditary Colorectal Cancer.- Hereditary Breast and Ovarian Cancer.- The Molecular Basis of Prostate Carcinogenesis.- Molecular Basis of Lung Carcinogenesis.- The Molecular Basis of Skin Carcinogenesis.- The Molecular Biology of Leukemias.- Molecular Mechanisms in Non-Hodgkin Lymphoma.- The Molecular Pathology of Head and Neck Squamous Cell Carcinoma.- Ovarian Cancer.- Molecular Pathology of Bone and Soft Tissue Tumors.- The Molecular Biology of Human Brain Tumors.- Cancer Drug Discovery and Anticancer Drug Development.- Biological Principles and Clinical Application of EGFR Inhibitors in Cancer.- Targeting Oncoproteins for Molecular Cancer Therapy.- Therapeutic Agents that Inhibit Angiogenesis.- Small Molecule Inhibitors.- Molecular Detection and Diagnosis of Cancer.- Gene Therapy in the Treatment of Human Cancer.- Personalized Medicine for the Treatment of Human Cancer.
Cancer Epidemiology: Incidence and Etiology of Human Neoplasms.- Essential Concepts and Techniques in Molecular Biology.- Cancer Genomics.- Cancer Cytogenetics.- The Epigenetic Basis of Human Cancer.- Cancer Proteomics.- An Overview of Cancer Genes.- Oncogenes and the Initiation and Maintenance of Tumorigenesis.- Positive Mediators of Cell Proliferation in Neoplasia: Growth Factors and Receptors.- Senescence, Apoptosis, and Cancer.- Novel Cancer Therapies Targeting Angiogenesis.- Beyond the Primary Tumor: Progression, Invasion, and Metastasis.- Simple Sequence Mutations.- Single Nucleotide Polymorphisms and Cancer Susceptibility.- Chromosomes and Chromosomal Instability in Human Cancer.- Epigenetic Mechanisms in Cancer Development.- MicroRNAs and Cancer.- Erionite and Asbestos in the Pathogenesis of Human Malignant Mesotheliomas.- Viral Mechanisms in Human Carcinogenesis.- Hormonal Carcinogenesis: The Role of Estrogens.- Sporadic Cancers.- Hereditary Cancer.- Retinoblastoma: Clinical and Molecular Perspectives.- Xeroderma Pigmentosum and the DNA Damage Response to Ultraviolet Light.- Hereditary Colorectal Cancer.- Hereditary Breast and Ovarian Cancer.- The Molecular Basis of Prostate Carcinogenesis.- Molecular Basis of Lung Carcinogenesis.- The Molecular Basis of Skin Carcinogenesis.- The Molecular Biology of Leukemias.- Molecular Mechanisms in Non-Hodgkin Lymphoma.- The Molecular Pathology of Head and Neck Squamous Cell Carcinoma.- Ovarian Cancer.- Molecular Pathology of Bone and Soft Tissue Tumors.- The Molecular Biology of Human Brain Tumors.- Cancer Drug Discovery and Anticancer Drug Development.- Biological Principles and Clinical Application of EGFR Inhibitors in Cancer.- Targeting Oncoproteins for Molecular Cancer Therapy.- Therapeutic Agents that Inhibit Angiogenesis.- Small Molecule Inhibitors.- Molecular Detection and Diagnosis of Cancer.- Gene Therapy in the Treatment of Human Cancer.- Personalized Medicine for the Treatment of Human Cancer.
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