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After nearly 4 years of working in HIV and AIDS field, I have studied the whole episode from different parts of the world. My experience of being born and grown up in Africa, where nearly 22.5 million people are living with HIV and AIDS and has only 10% of world's population (UNAIDS/WHO,2008) and my working experience in England for nearly seven years have taught me that, the developed world approaches towards HIV Pandemic are quite different from that of developing World. The review of educational approach on HIV awareness, prevention, treatment and care management reveals that there are health inequalities between the developed and developing worlds (Pratt, 2003). In addition I have learned that the attitudes of us, Africans, towards HIV and AIDS need to change in order to effectively promote HIV/AIDS Prevention intervention in the communities, starting from the grassroots through to the government levels. The prevention Intervention of HIV in the developed world has been successful due to various opportunities and strengths including economy, technology and communities' accessibility to education which, have much influence in combating HIV and AIDS Pandemic.