Yau-Huei Wei / Horng-Mo Lee / Chung Y. Hsu

The Role of Mitochondria in Human Aging and Disease

From Genes to Cell Signaling, Volume 1042
Herausgeber: Wei, Yau-Huei; Hsu, Chung Y; Lee, Horng-Mo

• Broschiertes Buch

Produktbeschreibung

Virtually every aspect of mitochondrial research and medicine is addressed in this volume, including mitochondrial function and dysfunction, free radical biology relevant to mitochondrial dysfunction, the role of mitochondria in apoptosis, and abnormal signaling processes and disease mechanisms associated with aging, mtDNA mutations, or mitochondrial damage. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

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Produktdetails

• Verlag: Wiley
• Volume 1042 edition
• Seitenzahl: 540
• Erscheinungstermin: 4. August 2006
• Englisch
• Abmessung: 229mm x 152mm x 30mm
• Gewicht: 795g
• ISBN-13: 9781573315425
• ISBN-10: 1573315427
• Artikelnr.: 23516433

Autorenporträt

Yau-Huei Wei is the editor of The Role of Mitochondria in Human Aging and Disease: From Genes to Cell Signaling, Volume 1042, published by Wiley. Horng-Mo Lee is the editor of The Role of Mitochondria in Human Aging and Disease: From Genes to Cell Signaling, Volume 1042, published by Wiley.

Inhaltsangabe

Preface: Yau
Huei Wei, Horng
Mo Lee, and Chung Y. Hsu. Part I: Mitochondrial Disease Models:. 1. Mitochondria
Based Model for Fetal Origin of Adult Disease and Insulin Resistance: Hong Kyu Lee, Kyong Soo Park, Young Min Cho, Yun Yong Lee, and Youngmi Kim Pak. 2. Evolutional Analysis in Determining Pathogenic versus Nonpathogenic Mutations of ATPase 6 in Human Mitochondriopathy: Chin
Yuan Tzen and Tsu
Yen Wu. 3. Restoration of Mitochondrial Function in Cells with Complex I Deficiency: Yidong Bai, Jeong Soon Park, Jian
Hong Deng, Youfen Li, and Peiqing Hu. 4. Hearing Loss in Mitochondrial Disorders: Chang
Hung Hsu, Haeyoung Kwon, Cherng
Lih Perng, Ren
Kui Bai, Pu Dai, and Lee
Jun C. Wong. 5. Brain Single Photon Emission Computed Tomography in Patients with A3243G Mutation in Mitochondrial DNA tRNA: Peterus Thajeb, Ming
Che Wu, Bing
Fu Shih, Chin
Yuan Tzen, Ming
Fu Chiang, and Rey
Yue Yuan. 6. Upregulation of Matrix Metalloproteinase 1 and Disruption of Mitochondrial Network in Skin Fibroblasts of Patients with MERRF Syndrome: Yi
Shing Ma, Yin
Chiu Chen, Ching
You Lu, Chun
Yi Liu, and Yau
Huei Wei. 7. Increased Oxidative Damage with Altered Antioxidative Status in Type 2 Diabetic Patients Harboring the 16189 T to C Variant of Mitochondrial DNA: Tsu
Kung Lin, Shang
Der Chen, Pei
Wen Wang, Yau
Huei Wei, Cheng
Feng Lee, Tzu
Ling Chen, Yao
Chung Chuang, Teng
Yeow Tan, Ku
Chou Chang, and Chia
Wei Liou. 8. Alteration of the Copy Number of Mitochondrial DNA in Leukocytes of Patients with Hyperlipidemia: Chin
San Liu, Ching
Ling Kuo, Wen
Ling Cheng, Ching
Shan Huang, Cheng
Feng Lee, and Yau
Huei Wei. 9. A New Noninvasive Test to Detect Mitochondrial Dysfunction of Skeletal Muscles in Progressive Supranuclear Palsy: Yung
Yee Chang, Chiang
Hsuan Lee, Min
Yu Lan, Hsiu
Shan Wu, Chiung
Chih Chang, and Jia
Shou Liu. 10. High Prevalence of the COII/tRNALys Intergenic 9
bp Deletion in Mitochondrial DNA of Taiwanese Patients with MELAS or MERRF Syndrome: Chin
San Liu, Wen
Ling Cheng, Yi
Yun Chen, Yi
Shing Ma, Cheng
Yoong Pang, and Yau
Huei Wei. . Part II: Mitochondrial Genome:. 11. Analysis of Proteome Bound to D
Loop Region of Mitochondrial DNA by DNA
Linked Affinity Chromatography and Reverse
Phase Liquid Chromatography/Tandem Mass Spectrometry: Yon
Sik Choi, Bo
Kyung Ryu, Hye
Ki Min, Sang
Won Lee, and Youngmi Kim Pak. 12. Mitochondrial Transcription Factor A in the Maintenance of Mitochondrial DNA: Overview of Its Multiple Roles: Dongchon Kang and Naotaka Hamasaki. 13. Mitochondrial Genome Instability and mtDNA Depletion in Human Cancers. By Hsin
Chen Lee, Pen
Hui Yin, Jin
Ching Lin, Cheng
Chung Wu, Chih
Yi Chen, Chew
Wun Wu, Chin
Wen Chi, Tseng
Nip Tam, and Yau
Huei Wei. 14. Frequent Occurrence of Mitochondrial Microsatellite Instability in the D
Loop Region of Human Cancers: Yue Wang, Vincent W.S. Liu, Hextan Y.S. Ngan, and Phillip Nagley. 15. Analysis of Heteroplasmy in Hypervariable Region II of Mitochondrial DNA in Maternally Related Individuals: Mei
Chen Lo, Horng
Mo Lee, Ming
Wei Lin, and Chin
Yuan Tzen. 16. Deleted Mitochondrial DNA in Human Luteinized Granulosa Cells: Heng
Kien Au, Shyh
Hsiang Lin, Shih
Yi Huang, Tien
Shun Yeh, Chii
Ruey Tzeng, and Rong
Hong Hsieh. 17. Identification of Human
Specific Adaptation Sites of ATP6: Bey
Liing Mau, Horng
Mo Lee, and Chin
Yuan Tzen. . Part III: Mitochondrial Function:. 18. Repeated Ovarian Stimulations Induce Oxidative Damage and Mitochondrial DNA Mutations in Mouse Ovaries: Hsiang
Tai Chao, Shu
Yu Lee, Horng
Mo Lee, Tien
Ling Liao, Yau
Huei Wei, and Shu
Huei Kao. 19. Calcium Stimulates Mitochondrial Biogenesis in Human Granulosa Cells: Tien
Shun Yeh, Jau
Der Ho, Vivian Wei
Chung Yang, Chii
Ruey Tzeng, and Rong
Hong Hsieh. 20. Dynamics of Mitochondria and Mitochondrial Ca2+ near the Plasma Membrane of PC12 Cells: A Study by Multimode Microscopy: De
Ming Yang, Chung
Chih Lin, Hsia Yu Lin, Chien
Chang Huang, Din Ping Tsai, Chin
Wen Chi, and Lung
Sen Kao. 21. Propofol Specifically Inhibits Mitochondrial Membrane Potential but Not Complex I NADH Dehydrogenase Activity, Thus Reducing Cellular ATP Biosynthesis and Migration of Macrophages: Gong
Jhe Wu, Yu
Ting Tai, Ta
Liang Chen, Li
Ling Lin, Yune
Fang Ueng, and Ruei
Ming Chen. 22. Abnormal Mitochondrial Structure in Human Unfertilized Oocytes and Arrested Embryos: Heng
Kien Au, Tien
Shun Yeh, Shu
Huei Kao, Chii
Ruey Tzeng, and Rong
Hong Hsieh. 23. Oxidative Damage and Mitochondrial DNA Mutations with Endometriosis: Shu
Huei Kao, Hsieng
Chiang Huang, Rong
Hong Hsieh, Su
Chee Chen, Ming
Chuan Tsai, and Chii
Reuy Tzeng. 24. Neuroprotective Role of Coenzyme Q10 against Dysfunction of Mitochondrial Respiratory Chain at Rostral Ventrolateral Medulla during Fatal Mevinphos Intoxication in the Rat: F C.H. LI, H P TSENG, and A Y.W. Chang. . Part IV: Oxidative Stress:. 25. Mitochondrial Dysfunction and Oxidative Stress as Determinants of Cell Death/Survival in Stroke: Pak H. Chan. 26. Oxidative Damage in Mitochondrial DNA Is Not Extensive: Kok Seong Lim, Kandiah Jeyaseelan, Matthew Whiteman, andrew Jenner, and Barry Halliwell. 27. Enhanced Generation of Mitochondrial Reactive Oxygen Species in Cybrids Containing 4977
bp Mitochondrial DNA Deletion: Mei
Jie Jou, Tsung
I Peng, Hong
Yueh Wu, and Yau
Huei Wei. 28. S
Nitrosoglutathione and Hypoxia
Inducible Factor
1 Confer Chemoresistance against Carbamoylating Cytotoxicity of BCNU in Rat C6 Glioma Cells: Ding
I Yang, Shang
Der Chen, Jiu
Haw Yin, and Chung Y. Hsu. 29. Celecoxib Induces Heme
Oxygenase Expression in Glomerular Mesangial Cells: Chun
Cheng Hou, Su
Li Hung, Shu
Huei Kao, Tso Hsiao Chen, and Horng
Mo Lee. 30. Oxidative Stress
Induced Depolymerization of Microtubules and Alteration of Mitochondrial Mass in Human Cells: Cheng
Feng Lee, Chun
Yi Liu, Rong
Hong Hsieh, and Yau
Huei Wei. 31. Blood Lipid Peroxides and Muscle Damage Increased following Intensive Resistance Training of Female Weightlifters: Jen
Fang Liu, Wei
Yin Chang, Kuei
Hui Chan, Wen
Yee Tsai, Chen
Li Lin, and Mei
Chieh Hsu. 32. Anti
Inflammatory and Antioxidative Effects of Propofol on Lipopolysaccharide
Activated Macrophages: Ruei
Ming Chen, Tyng
Guey Chen, Ta
Liang Chen, Li
Ling Lin, Chia
Chen Chang, Hwa
Chia Chang, and Chih
Hsiung Wu. 33. Protective Effect of
Keto
ß
Methyl
n
Valeric Acid on BV
2 Microglia under Hypoxia or Oxidative Stress: Hsueh
Meei Huang, Hsio
Chung Ou, Huan
Lian Chen, Rolis Chien
Wei Hou, and Kee Ching G. Jeng. 34. Oxidative Toxicity in BV
2 Microglia Cells: Sesamolin Neuroprotection of H2O2 Injury Involving Activation of p38 Mitogen
Activated Protein Kinase: Rolis Chien
Wei Hou, Chia
Chuan Wu, Jing
Rong Huang, Yuh
Shuen Chen, and Kee
Ching G. Jeng. 35. Angiotensin II Stimulates Hypoxia
Inducible Factor 1 Accumulation in Glomerular Mesangial Cells: Tso
Hsiao Chen, Jin
Fong Wang, Paul Chan, and Horng
Mo Lee. 36. Effects of Glucose and
Tocopherol on Low
Density Lipoprotein Oxidation and Glycation: Chun
Jen Chang, Rong
Hong Hsieh, Hui
Fang Wang, Mei
Yun Chin, and Shih
Yi Huang. 37. Identification of Three Mutations in the Cu,Zn
Superoxide Dismutase (Cu,Zn
SOD) Gene with Familial Amyotrophic Lateral Sclerosis: Transduction of Human Cu,Zn
SOD into PC12 Cells by HIV
1 TAT Protein Basic Domain: Chih
Ming Chou, Chang
Jen Huang, Chwen
Ming Shih, Yi
Ping Chen, Tsang
Pai Liu, and Chien
Tsu Chen. 38. Kainic Acid
Induced Oxidative Injury Is Attenuated by Hypoxic Preconditioning: Cheng
Hao Wang, Anyu Chang, May
Jywan Tsai, Henrich Cheng, Li
Ping Liao, and Anya Maan
Yuh Lin. 39. Antioxidant N
Acetylcysteine Blocks Nerve Growth Factor
Induced H2O2/ERK Signaling in PC12 Cells: Liang
Yo Yang, Wun
Chang Ko, Chun
Mao Lin, Jia
Wei Lin, Jen
Chine Wu, Chien
Ju Lin, Huey
Hwa Cheng, and Chwen
Ming Shih. . Part V: Antioxidants:. 40. Effect of Enhanced Prostacyclin Synthesis by Adenovirus
Mediated Transfer on Lipopolysaccharide Stimulation in Neuron
Glia Cultures: May
Jywan Tsai, Song
Kun Shyue, Ching
Feng Weng, Ying Chung, Dann
Ying Liou, Chi
Ting Huang, Huai
Sheng Kuo, Meng
Jen Lee, Pei
Teh Chang, Ming
Chao Huang, Wen
Cheng Huang, K D Liou, and Henrich Cheng. 41. Potential Mechanism of Blood Vessel Protection by Resveratrol, a Component of Red Wine: Huei
Mei Huang, Yu
Chih Liang, Tzu
Hurng Cheng, Cheng
Heien Chen, and Shu
Hui Juan. 42. Pravastatin Attenuates Ceramide
Induced Cytotoxicity in Mouse Cerebral Endothelial Cells with HIF
1 Activation and VEGF Upregulation: Shang
Der Chen, Chaur
Jong Hu, Ding
I Yang, Abdullah Nassief, Hong Chen, Kejie Yin, Jan Xu, and Chung Y. Hsu. 43. Alleviation of Oxidative Damage in Multiple Tissues in Rats with Streptozotocin
Induced Diabetes by Rice Bran Oil Supplementation: Rong
Hong Hsieh, Li
Ming Lien, Shyh
Hsiang Lin, Chia
Wen Chen, Huei
Ju Cheng, and Hsing
Hsien Cheng. 44. Curcumin Inhibits ROS Formation and Apoptosis in Methylglyoxal
Treated Human Hepatoma G2 Cells: Wen
Hsiung Chan, Hsin
Jung Wu, and Yan
Der Hsuuw. 45. Prevention of Cellular Oxidative Damage by an Aqueous Extract of Anoectochilus formosanus: Leng
Fang Wang, Chun
Mao Lin, Chwen
Ming Shih, Hui
Ju Chen, Borcherng Su, Cheng
Chuang Tseng, Bao
Bih Gau, and Kur
Ta Cheng. 46. Inhibitory Effects of a Rice Hull Constituent on Tumor Necrosis Factor , Prostaglandin E2, and Cyclooxygenase
2 Production in Lipopolysaccharide
Activated Mouse Macrophages: Sheng
Tung Huang, Chien
Tsu Chen, Kur
Ta Chieng, Shih
Hao Huang, Been
Huang Chiang, Leng
Fang Wang, Hsien
Saw Kuo, and Chun
Mao Lin. 47. Raffinee in the Treatment of Spinal Cord Injury: An Open
Labeled Clinical Trial: Hsin
Ying Chen, Jer
Min Lin, Hung
Yi Chuang, and Wen
Ta Chiu. . Part VI: Apoptosis:. 48. Induction of Thioredoxin and Mitochondrial Survival Proteins Mediates Preconditioning
Induced Cardioprotection and Neuroprotection: Chuang C. Chiueh, Tsugunobu andoh, and P Boon Chock. 49. Mitochondrion
Targeted Photosensitizer Enhances the Photodynamic Effect
Induced Mitochondrial Dysfunction and Apoptosis: Tsung
I Peng, Cheng
Jen Chang, Mei
Jin Guo, Yu
Huai Wang, Jau
Song Yu, Hong
Yueh Wu, and Mei
Jie Jou. 50. Attenuation of UV
Induced Apoptosis by Coenzyme Q10 in Human Cells Harboring Large
Scale Deletion of Mitochondrial DNA: Cheng
Feng Lee, Chun
Yi Liu, Shu
Mei Chen, Marianna Sikorska, Chen
Yu Lin, Tzu
Ling Chen, and Yau
Huei Wei. 51. Antisense RNA to Inducible Nitric Oxide Synthase Reduces Cytokine
Mediated Brain Endothelial Cell Death: Ding
I Yang, Shawei Chen, Uthayashanker R. Ezekiel, Jan Xu, Yingji Wu, and Chung Y. Hsu. 52. 2,6
Diisopropylphenol Protects Osteoblasts from Oxidative Stress
Induced Apoptosis through Suppression of Caspase
3 Activation: Ruei
Ming Chen, Gong
Jhe Wu, Hwa
Chia Chang, Jue
Tai Chen, Tzeng
Fu Chen, Yi
Ling Lin, and Ta
Liang Chen. 53. Nitric Oxide Induces Osteoblast Apoptosis through a Mitochondria
Dependent Pathway: Wei
Pin Ho, Ta
Liang Chen, Wen
Ta Chiu, Yu
Ting Tai, and Ruei
Ming Chen. 54. Bcl
2 Gene Family Expression in the Brain of Rat Offspring after Gestational and Lactational Dioxin Exposure: Shwu
Fen Chang, Yu
Yo Sun, Liang
Yo Yang, Ssu
Yao Hu, Shih
Ying Tsai, Wen
Sen Lee, and Yi
Hsuan Lee. 55. IL
5 Inhibits Apoptosis by Upregulation of c
myc Expression in Human Hematopoietic Cells: Shu
Hui Juan, Jeffrey Jong
Young Yen, Horng
Mo Lee, and Huei
Mei Huang. 56. Detection of Apoptosis and Necrosis in Normal Human Lung Cells Using 1H NMR Spectroscopy: Chwen
Ming Shih, Wun
Chang Ko, Liang
Yo Yang, Chien
Ju Lin, Jui
Sheng Wu, Tsui
Yun Lo, Shwu
Huey Wang, and Chien
Tsu Chen. 57. Cadmium Toxicity toward Caspase
Independent Apoptosis through the Mitochondria
Calcium Pathway in mtDNA
Depleted Cells: Yung
Luen Shih, Chien
Ju Lin, Sheng
Wei Hsu, Sheng
Hao Wang, Wei
Li Chen, Mei
Tsu Lee, Yau
Huei Wei, and Chwen
Ming Shih. 58. Pectinesterase Inhibitor from Jelly Fig (Ficus awkeotsang Makino) Achene Induces Apoptosis of Human Leukemic U937 Cells: Jia
Huei Chang, Yuh
Tai Wang, and Hung
Min Chang. 59. Enhancement of Cisplatin
Induced Apoptosis and Caspase 3 Activation by Depletion of Mitochondrial DNA in a Human Osteosarcoma Cell Line: Hsiu
Chuan Yen, Yi
Chia Tang, Fan
Yi Chen, Shih
Wei Chen, and Hideyuki J. Majima. 60. Thallium Acetate Induces C6 Glioma Cell Apoptosis: Chee
Fah Chia, Soul
Chin Chen, Chin
Shyang Chen, Chuen
Ming Shih, Horng
Mo Lee, and Chih
Hsiung Wu. 61. Effects of Gonadotrophin
Releasing Hormone Agonists on Apoptosis of Granulosa Cells: Nu
Man Tsai, Rong
Hong Hsieh, Heng
Kien Au, Ming
Jer Shieh, Shih
Yi Huang, and Chii
Ruey Tzeng