The Role of Pendrin in Health and Disease
Broschiertes Buch

The Role of Pendrin in Health and Disease

Molecular and Functional Aspects of the SLC26A4 Anion Exchanger

Herausgegeben: Dossena, Silvia; Paulmichl, Markus
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This book reviews the current state of knowledge on the genetics, molecular biology and physiology of pendrin, with a particular focus on pendrin dysfunction and the consequences for human health.Pendrin is a membrane transport protein expressed in the thyroid, inner ear, kidney and airways, and was recently found in a variety of other tissues and organs. Pendrin malfunction may cause a genetic disease called Pendred syndrome or non-syndromic deafness.The book provides a thorough description of the multifaceted role of pendrin in human health and disease. As such, it offers an invaluable tool ...