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In this Special Issue, we have invited authors with serious research in the field of the circular economy with interesting ideas for the recovery of waste products in various productions, but we have selected and published only the best articles with the latest results of research on the biological effects of waste products, studies of natural compounds, and looked at the mechanisms underlying their biological activity. We selected articles describing innovative experimental models related to the extraction and purification of natural functional components and their application and the danger of the presence of dangerous toxic substances, but we emphasized the beneficial properties of these extracts or their compounds and sought benefits in the prevention and treatment of various serious illnesses.