Rhes is a new protein that is highly expressed in the
striatal system of rodents. In the present book, it
is described experimental work about the role of this
protein in behaviors mediated by the striatal
dopaminergic system. Some of the behavioral
paradigms described are stereotypy, anxiety and basal
levels of activity. The mutant mice model used is
the rhes ko mice. Female groups are included for all
the experiments. Very interesting gender differences
are found in anxiety and stereotypy. The present
work give evidence of the role of rhes protein in
dopamine receptor supersensitivity; this is relevant
for conditions like schizophrenia, Parkinson disease,
ADHD and others. This book represents one of the few
works that have been performed in the role of rhes
protein in behavioral neuroscience.
striatal system of rodents. In the present book, it
is described experimental work about the role of this
protein in behaviors mediated by the striatal
dopaminergic system. Some of the behavioral
paradigms described are stereotypy, anxiety and basal
levels of activity. The mutant mice model used is
the rhes ko mice. Female groups are included for all
the experiments. Very interesting gender differences
are found in anxiety and stereotypy. The present
work give evidence of the role of rhes protein in
dopamine receptor supersensitivity; this is relevant
for conditions like schizophrenia, Parkinson disease,
ADHD and others. This book represents one of the few
works that have been performed in the role of rhes
protein in behavioral neuroscience.