A. F. Casy

The Steric Factor in Medicinal Chemistry

Dissymmetric Probes of Pharmacological Receptors

• Gebundenes Buch

Produktbeschreibung

'It is indeed the merit of Dr. Alan F. Casy to bring in these pages a clear and comprehensive view of medicinal stereochemistry, a discipline in which he has been active and successful for many years both as a teacher and a researcher. Written for graduate students and research workers in medicinal chemistry and pharmacology, this book will contribute significantly towards a better education of scientists by removing the fear of stereochemistry caused by ignorance, moderating the overconfidence of possible zealots, and outlining a broader context.'-from the foreword by Bernard Testa

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Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 978-0-306-44289-6
• 1993.
• Seitenzahl: 596
• Erscheinungstermin: 31. Dezember 1993
• Englisch
• Abmessung: 241mm x 160mm x 37mm
• Gewicht: 1007g
• ISBN-13: 9780306442896
• ISBN-10: 0306442892
• Artikelnr.: 23133269

Inhaltsangabe

1. Introduction.- 2. Nomenclature and Methodology.- 3. Pharmacokinetics: Including Use of Racemic Mixtures in Therapy.- 4. Adrenergic Ligands: Chiefly Agonists.- 5. Adrenoceptor Antagonists.- 6. Dopamine and Dopaminergic Ligands.- 7. Dopamine Antagonists.- 8. Cholinergic Agonists.- 9. Muscarinic Antagonists.- 10. Ligands of Nicotinic Cholinergic Receptors (nAChR) Including Neuromuscular Blocking Agents.- 11. Histamine Receptors: Agonists and Antagonists.- 12. 5-Hydroxytryptamine Ligands.- 13. Opioid Ligands: Part 1.- 14. Opioid Ligands: Part 2.- Appendix and Postscript.