Many sports and strenuous exercises are associated with some degree of muscle damage, pain and fatigue that can lead to poor athletic progress, therefore the need for recovery speeding methods has been increasingly demanded.The use of performance enhancing nutritional supplements to improve athletic performance has been increasing during the previous decades. Supplementation with vitamins and minerals in excess of recommended daily allowances has been increasingly reported to have no effect on muscle mass or athletic performance, and the need to identify evidence-based sport supplements has been increasingly demanded. The aim of this book is to provide an overview of the use of creatine in sport research progress.