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Study on heart, the biological marvel has always been a fundamental topic in anatomy and physiology books. This textbook is an amalgamation of modern views on structure, types, development, and function of heart in different vertebrate groups for the undergraduate student of Zoology / Life Science who needs a general understanding of the vertebrate heart. A basic background in embryology, anatomy and physiology is assumed. Though there is a touch of general concept which address structural and functional aspects of heart in both invertebrates and vertebrates but all chapters are mainly concerned with five classes of vertebrates. Both developmental and anatomical aspects are discussed here because the discussion from both perspectives can only enhance our understanding of functional and evolutionary aspects of such organ in different vertebrate groups with increasing complexity. This book may prove useful to zoologists and those with a genuine interest in the comparative account of heart.