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Focusing on three forms of biological threat--bioterrorism, biocrime and biohacking--the author examines the history of biowarfare and terrorism. Groups drawn to biological aggression are discussed, along with the array of viruses, bacteria and toxins they might use in their attacks. The phenomenon of biocrime--biological aggression targeting individuals for personal rather than ideological reasons--is explored, along with the growing trend of biohacking. Part II presents case studies of bioterrorism and biocrime from the United States and Japan.