Majid Amini Khorasgani, Sahar Naderi Vahed

The world of microRNA-202-3P, ADA Gene and multiple sclerosis

Targeting miRNA in multiple sclerosis

• Broschiertes Buch

Produktbeschreibung

One of the latest studies in the genetics field is the evaluation of role of micro-RNAs as a biomarker for diagnosis of multiple sclerosis (MS), which is a demyelinating disease of the central nervous system (CNS) and emerges in the form of numerous small and large plaques in white matter in the brain and spinal cord. This disease could be associated with several complications, including reduced vision, spasticity and imbalance, and impaired sphincter control. MiR-202-3p is an intronic miRNA located in the ADA (Adenosine Deaminase) gene, which is the main enzyme involved in the pathway for the conversion of adenosine into inosine. Moreover, ADA regulates the inflammatory response and protection of tissue from damage as a strong complementary mechanism. This study aimed to evaluate the expression level of miR-202-3p in individuals diagnosed with relapsing-remitting multiple sclerosis (RRMS) and healthy individuals in Isfahan, Iran.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 92
• Erscheinungstermin: 12. Mai 2020
• Englisch
• Abmessung: 220mm x 150mm x 6mm
• Gewicht: 155g
• ISBN-13: 9786202555234
• ISBN-10: 6202555238
• Artikelnr.: 59570373

Autorenporträt

Majid Amini Khorasgangani. Tiene una licenciatura en microbiología y una maestría en genética y ha estado trabajando en el laboratorio y la industria farmacéutica desde 2011. Después de trabajar en este campo durante algún tiempo, encontró interés en la investigación de la EM y las enfermedades psiquiátricas y publicó varios artículos en estos campos.