The Yersinia story - Pham, Jeanette
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European Yersinia enterocolitica 4/O:3 produce two types of -lactamases, enzyme A and enzyme B and belong to phage type VIII (4/O:3/VIII). Y. enterocolitica 4/O:3 isolated in Canada and Australia are identical producing only enzyme A and belonging to the same phage type IXb (4/O:3/IXb/A). Their failure to express enzyme B is due to same defect in ampC gene. When unusual European Y. enterocolitica 4/O:3 strains fail to produce enzyme B, it is invariably due to a different defect in ampC gene. The difference in defective ampC gene between European and Canadian/Australian 4/O:3 shows that the…mehr

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Produktbeschreibung
European Yersinia enterocolitica 4/O:3 produce two types of -lactamases, enzyme A and enzyme B and belong to phage type VIII (4/O:3/VIII). Y. enterocolitica 4/O:3 isolated in Canada and Australia are identical producing only enzyme A and belonging to the same phage type IXb (4/O:3/IXb/A). Their failure to express enzyme B is due to same defect in ampC gene. When unusual European Y. enterocolitica 4/O:3 strains fail to produce enzyme B, it is invariably due to a different defect in ampC gene. The difference in defective ampC gene between European and Canadian/Australian 4/O:3 shows that the latter group did not derive from the former. The presence of the predominant and unique Y. enterocolitica subtype 4/O:3/IXb/A at two areas far apart on the earth can only be explained by a common geographical origin. This provides a microbiological proof of linkages between Paleoproterozoic and Mesoproterozoic geological features in north western Canada and Australia. The manuscript presents a new insight and perspective to both Geology and Microbiology.
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Autorenporträt
Dr. Jeanette Pham obtained her PhD degree in Microbiology in 1994. She is the author of several articles on Yersinia enterocolitica published in peer reviewed International Journals. She is the Senior Scientist in charge of the Reference Laboratory of the CDS method of Antibiotic Susceptibility Testing, Sydney, Australia.