Therapies for Treatment-Resistant Depression

Neuropharmacology and Neurostimulation
Herausgeber: Murrough, James; Charney, Dennis

• Broschiertes Buch

Produktbeschreibung

Therapies for Treatment-Resistant Depression: Neuropharmacology and Neurostimulation provides readers with an authoritative, comprehensive and targeted treatment guide. The first section reviews the essential knowledge and methods of clinical neuroscience and neuropsychopharmacological techniques as they apply to novel treatment discovery for depression. This is followed by detailed chapters on ketamine, esketamine, other glutamate modulators in development, GABA modulators, neuropeptides, anti-inflammatory agents, and other classes of novel therapeutics under study for TRD and related mood disorders. The last section consists of a set of chapters of special interest that includes current and future research directions, development of psilocybin-based interventions and other psychedelic compounds currently under study for TRD and advances in biomarker-guided and personalized treatment. Edited by world renowned experts in the field, this book is the ultimate resource for researchers and clinicians.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 425
• Erscheinungstermin: 1. August 2025
• Englisch
• ISBN-13: 9780443160059
• ISBN-10: 0443160058
• Artikelnr.: 70205780

Inhaltsangabe

1. Introduction 2. Treatment-Resistant Depression: Epidemiology and
Clinical Presentation 3. Molecular Neuropharmacology of Treatment-Resistant
Depression 4. Neurobiology and Neuroimaging of Treatment-Resistant
Depression 5. Pharmacotherapy of Treatment-Resistant Depression: Overview
and Look Ahead 6. Lithium, Dopamine Modulators, and Other Augmentation
Strategies for Treatment-Resistant Depression 7. Ketamine and Esketamine
for Treatment-Resistant Depression 8. The Impact of Inflammation on
Treatment Resistance in Depression: Mechanisms and Translational
Opportunities 9. Novel Pharmacotherapies for Treatment-Resistant
Depression: A Focus on Glutamate and GABA Modulators 10. Electroconvulsive
Therapy for Treatment-Resistant Depression 11. Transcranial Magnetic
Stimulation for Treatment-Resistant Depression 12. Vagal Nerve Stimulation
for Treatment-Resistant Depression 13. Deep Brain Stimulation for
Treatment-Resistant Depression 14. Psilocybin and Other Psychedelic Agents
in Development for Treatment-Resistant Depression 15. Neuroimaging
Biomarkers in Treatment Selection for Treatment-Resistant Depression 16.
The Role of Genetics in Treatment-Resistant Depression