Globally, buildings account for almost half of the energy use in both developed and developing nations. Commercial buildings account for a sizeable proportion of this building energy consumption and this trend will probably continue to increase. Therefore, concerted efforts are currently being directed at the development and application of effective building strategies and measures to improve energy efficiency in buildings. This work evaluates the impact of various energy efficiency measures and technologies on the thermal and energy performance of UK hotel buildings using a whole building dynamic simulation software with a focus on the knock-on effects that these technologies will have on the overall energy performance and efficiency of UK hotels, either installed individually or in various combinations.