Theivendren Panneer Selvam, Caiado Richa James, Sivakumar Arumugam

Thiazole - An Active Scaffold against Bacterial Strains

Novel Thiazole Derivatives

• Broschiertes Buch

Produktbeschreibung

A series of Ethyl-3-methyl-5-(substituted-phenyl)-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b]quinazoline-2-carboxylate derivatives have been synthesize from cyclohexanone and substituted benzaldehyde with the aim of developing potential antimicrobials and antitubercular agents. It was characterized by FT-IR, 1H NMR and Mass spectroscopy. All the newly synthesized compounds were screened for their antimicrobial and antifungal activities on Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus cereus (Gram-positive bacteria), Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia (Gram-negative bacteria), Aspergillus fumigates, Candida albicans (Fungi). All the synthesized compounds were also evaluated for their antitubercular activity against Mycobacterium tuberculosis strain H37Ra.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 200
• Erscheinungstermin: 14. Juli 2013
• Englisch
• Abmessung: 220mm x 150mm x 12mm
• Gewicht: 316g
• ISBN-13: 9783659324390
• ISBN-10: 3659324396
• Artikelnr.: 39143038

Autorenporträt

Dr. T. Panneerselvam Is working as an Associate Professor in Arulmigu Kalasalingam College of Pharmacy, Krishnankoil, Tamilnadu. He earned Young Faculty Award 2014 and he has 08 years of teaching and research experience. His research has focused on the Design, Synthesis, and Analytical/Biological Screening of Novel Heterocyclic Derivatives.