Lawrence J. Berliner (ed.)

Thrombin

Herausgegeben von Berliner, Lawrence J.

• Gebundenes Buch

Produktbeschreibung

This comprehensive treatise details the structure, biochemistry, and physiology of thrombin, including detailed three-dimensional X-ray structures of inhibited human thrombin complexes. It is both well-illustrated and well-referenced to provide the physiologist and the biochemist with a first-rate sourcebook.

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Produktdetails

• Verlag: Springer, Berlin
• 1992.
• Seitenzahl: 460
• Erscheinungstermin: 30. November 1992
• Englisch
• Abmessung: 235mm x 157mm x 31mm
• Gewicht: 780g
• ISBN-13: 9780306439919
• ISBN-10: 0306439913
• Artikelnr.: 24522225

Autorenporträt

Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.

Inhaltsangabe

Structure: Nuclear Magnetic Resonance Studies of ThrombinFibrinopeptide and ThrombinHirudin Complexes (F. Ni et al.). ESR and Flourescence Studies of Thrombin Active Site Conformation (L.J. Berliner). Biochemistry: Synthetic Substrates and Inhibitors of Thrombin (J.C. Powers, C.M. Kam). Regulation of Thrombin by Antithrombin and Heparin Cofactor II (S.T. Olson, I. Björk). Hirudin Interactions with Thrombin (S.R. Stone, J.M. Maraganore). Physiology: Functional Domains in Thrombin Outside the Catalytic Site (R. BarShavit et al.). Post Clotting Cellular Effects of Thrombin Mediated by Interaction with HighAffinity Thrombin Receptors (D.H. Carney). Regulation of ThrombinInduced Endothelial Barrier Dysfunction and Prostaglandin Synthesis (J.G.N. Garcia et al.). 3 additional articles. Index.