A Typical Meteorological Year (TMY) was developed with a new method that combines the weighting factors of four sets of different TMY generators. The definition of the TMY is fundamental for the development of the climate file used by the Building Energy Simulation codes. This work is dedicated to the definition of the TMY in the city of Salta (1232 masl), Argentina, to be applied in the design of social housing, for sizing of photovoltaic systems, solar collectors, air and water heaters. It was based on data provided by the National Meteorological Service (SMN) of Argentina on various meteorological variables recorded at hourly intervals over 11 years (2006-2016). This book also presents the application of the TMY in social housing, using the SIMEDIF program, the energy demands for cooling and heating were estimated so that the interior of the house is within the comfort temperature range.