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The problem between sex and gender is a conflict that has repercussions in many fields of science including Medicine, Psychology and Education, being the focus of the study of authors such as Sigmund Freud and Jean Piaget. Childhood is a time of discovery for the child. But, how should parents act when the child believes that it is biologically what it is not, but, psychologically, acts as if it were? This is a disorder of identity known as Dysphoria of Gender or, popularly, Transexuality. Whose person believes he belongs to his opposite sex, not to his biological sex. The book presents some considerations on the concept of Dysphoria of Gender in human development, from childhood to some traits of adulthood, highlighting how parents should deal with the child transsexual, as well as the process of understanding of being male or female. Therefore, this is a subject of interest to educational, social, and cultural directed to educators, students, professionals of various areas or to any person that want to know a little more about the Dysphoria of Gender in childhood, whose love, respect and acceptance are key in this process.