Total synthesis of indole derivatives - Kachhot, Kanji;Vaghela, Foram
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Here a total synthesis of some 2-substituted indole derivatives like 2-phenyl indole and 1,2,3,4-tetrahydro carbazole and their N-protection by some new trial reagent as a Benzyl bromide and Allyl bromide successfully protect an indole derivatives and it gives a pure compound by Column chromatography method. also, synthesized Formylation by Vilsmaiyer-Hack reaction to attached aldehyde group on 3-position of substituted indole using of DMF+POCl3 reagent. These derivatives and methods could be helpful to fresh organic chemists who are willing to join synthesis work.

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Produktbeschreibung
Here a total synthesis of some 2-substituted indole derivatives like 2-phenyl indole and 1,2,3,4-tetrahydro carbazole and their N-protection by some new trial reagent as a Benzyl bromide and Allyl bromide successfully protect an indole derivatives and it gives a pure compound by Column chromatography method. also, synthesized Formylation by Vilsmaiyer-Hack reaction to attached aldehyde group on 3-position of substituted indole using of DMF+POCl3 reagent. These derivatives and methods could be helpful to fresh organic chemists who are willing to join synthesis work.
Autorenporträt
Kanji Kachhot é bolseiro de investigação no Departamento de Química da Universidade de Saurashtra. Trabalhou como investigador numa empresa farmacêutica. É especialista no domínio da síntese e da conceção. Pediu a patente de uma molécula ativa anti-cancro. Publicou 5 artigos internacionais em revistas de renome.