Towards Efficient Designing of Safe Nanomaterials

Innovative Merge of Computational Approaches and Experimental Techniques
Herausgeber: Leszczynski, Jerzy; Puzyn, Tomasz

• Gebundenes Buch

Produktbeschreibung

Nanotechnology is one of the most promising and rapidly-expanding areas of science and the development of new materials on the nanoscale can benefit many disciplines, including chemistry, physics, and medicine. However, novel nanomaterials can possess a negative impact on human health and the environment and their development should be accompanied by a comprehensive risk assessment. Until now, information on the methods available for this purpose has been fragmented. This book presents a comprehensive review of the latest achievements in risk-assessing novel nanomaterials, drawing on expertise from across the globe. Both empirical methodologies and computational techniques are presented, and the editors advise that both groups of techniques are required for a complete risk assessment. Anyone developing new nanomaterials (in academia or industry) will find this book an essential reference. Toxicologists and environmental scientists will also benefit from learning the latest tools used for detecting nanomaterials in the environment.

Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 378
• Erscheinungstermin: 27. September 2012
• Englisch
• Abmessung: 237mm x 162mm x 27mm
• Gewicht: 744g
• ISBN-13: 9781849734530
• ISBN-10: 1849734534
• Artikelnr.: 35892548

Autorenporträt

Jerzy Leszczynski is Professor of Chemistry and a President's Distinguished Fellow. Director of Interdisciplinary Nanotoxicity Center. Author and co-author of almost 700 peer-reviewed papers (H index 47) and 50 book chapters.

Inhaltsangabe

Nanomaterials: benefits and risks
Experimental characterizing structural properties of nanoparticles related to their toxicity
Structure-property mapping methods
Modelling properties of nanoparticles based on quantum-mechanical methods
Ontology
Empirical determination of nanoparticles' behavior in environmental media
Computational mass-ballance modeling of environmental transport and fate of engineered nanoparticles
Pharmacokinetics and biological fate of nanoparticles
Pharmacokinetic-based modeling
Modeling kinetics of nanoparticle cellular interaction and transport
Toxicity and Ecotoxicity testing of engineered nanoparticles - experimental point of view
In vitro toxicity of nanomaterials
In vivo testing
Computational modeling of interactions between nanoparticles and other species
Comprehensive Environmental Assessment as a Tool for Nanomaterial Risk Assessment
Predicting oxidative stress
Nano-QSAR