The long history of anti-Semitism began religious anti-Semitism between Judaism and The Early Church after the destruction of the Second Temple in 70 CE. Thus, religious discrimination varied through the Medieval Era, the Spanish Era through the nineteenth century. Thereupon, Racial anti-Semitism began with the introduction of pseudo-science, Eugenics, enabling the Nazi Regime 1933 - 1945, to eliminate those 'unworthy of life'. Such sub-humans included criminals, mental defectives, physical defective, Jews, Slavs, Gypsies and other non-Aryans. Accordingly, the Nazi regime sterilized more than 400,000 mental and physical defectives and gassed another 300,000 regardless of creed. Because of Anti-Semitism, the Nazi's murdered more than 6 million Jews, virtually emptying Europe of its Jews. It also killed 250,000 - 500,000 Roma gypsies, 1500 Jehovah's witness and 5.000 - 15,000 homosexuals.