Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems

Herausgegeben:Williams, Marc A.

• Gebundenes Buch

Produktbeschreibung

Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems

An indispensable compendium detailing the toxicology of nanoparticles with a focus on mechanisms, emerging issues, and new approaches

Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems provides authoritative information on the toxicology of ultrafine and nanoparticulate matter that contaminate terrestrial or aquatic environments and present unique challenges in applied public health and toxicological research. Detailed chapters by a panel of world-renowned experts examine the complementary and dynamic interdependence of aquatic, terrestrial, and human systems and the toxicological impacts on exposure to engineered and manufactured nanoparticles and nanomaterials.

Organized into four sections, the book opens with a thorough overview of the field, including known challenges and the necessity for current research activity. The second section describes terrestrial and aquatic systems and the ecotoxicological impact of nanomaterials, followed by critical analysis of the many human health effects of nanomaterials. The book concludes with an in-depth discussion of current gaps in knowledge, future directions, new approach methodologies, alternatives to animal models, and the emerging environmental threat from nanoplastics. Presenting case exemplars of the ecotoxicological impact of nanoparticles in aquatic and terrestrial systems, this important resource:
_ Presents in-depth coverage of ecosafety, environmental behavior, fate and transport, interactive effects with other contaminants, and current challenges in soil nano-ecotoxicology
_ Addresses rising concerns regarding air pollution and neurological disorders, and the roles played by the gastrointestinal system, the mucosal microbiome, and the immunotoxicology and vasculotoxicity of metal-based nanoparticles
_ Provides detailed coverage of nanomaterial health effects from both animal and in vitro models, including the gut microbiome, innate immunity, neurological and cardiovascular impacts, mechanisms of action, and hazard characterization
_ Analyzes key topics in ecological nanotoxicology such as environmental micro- and nano-plastic pollution and applied risk assessment

Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems is essential reading for toxicologists, applied biologists, ecotoxicologists, research scientists, medical professionals, regulators, and advanced students in fields such as public health, environmental ecotoxicology and medicine, immunotoxicology, neurotoxicology, cardiovascular and systems biology, hazard identification, and risk assessment.

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Produktdetails

• Verlag: Wiley / Wiley & Sons
• Artikelnr. des Verlages: 1W119316330
• 1. Auflage
• Seitenzahl: 496
• Erscheinungstermin: 13. Juli 2022
• Englisch
• Abmessung: 235mm x 157mm x 31mm
• Gewicht: 824g
• ISBN-13: 9781119316336
• ISBN-10: 1119316332
• Artikelnr.: 63198893

Autorenporträt

Marc A. Williams, PhD, is an immunotoxicologist and Project Manager for Ecotoxicological Assessment, U.S. Army Public Health Center, Directorate of Toxicology, Aberdeen Proving Ground, Maryland. He is the author of more than 100 peer-reviewed articles, papers, book chapters, book titles, and scientific reports, with research interests in environmental toxicology, nanotoxicology, immunotoxicology and public health. Dr Williams is the Editor-in-Chief of Drug and Chemical Toxicology and a regular editor for Toxicology Letters.

Inhaltsangabe

List of Contributors xv

Foreword xxi

Editor Biography xxiii

Section I Introduction 1

1 A One Health Perspective and Introduction 3
Marc A. Williams and Gunda Reddy

1.1 Background 3

1.2 Structural and Logical Organization of the Book 9

Acknowledgments 15

References 15

Section II Terrestrial and Aquatic Systems 19

2 Ecosafety of Nanomaterials in the Aquatic Environment 21
Maria J. Bebianno, Thiago L. Rocha, José P. Pinheiro, Margarida Ribau Teixeira, and Fernanda Cassio

2.1 Introduction 21

2.2 Inputs of NMs to the Aquatic Environment 23

2.3 HowWastewater Treatment Processes Act in the Removal of Nanomaterials? 23

2.4 So What Is Expected to Occur in WWTPs Processes? 24

2.5 The Importance of Understanding Speciation of NMs 27

2.6 Ecotoxicological Effects of NMs in Freshwater Organisms 30

2.7 Ecotoxicological Effects of NMs in Marine Organisms 34

2.8 Interactive Effects of NMs with Other Contaminants 38

2.9 Environmental Risk Assessment (ERA) of NMs 42

Acknowledgments 43

References 44

3 Changes in Toxicant Physicochemistry and Bioavailability During Sorption/Desorption Processes with TiO2 Nanoparticles in the Aqueous Phase 59
Danae Patsiou, Martin R. S. McCoustra, Teresa F. Fernandes, and Theodore B. Henry

3.1 Introduction 59

3.2 Properties of TiO2 NPs in the Aqueous Phase 61

3.2.1 Agglomeration 61

3.2.2 Oxidation of TiO2 NPs by UV Radiation 62

3.3 Sorption of Organic Substances to TiO2 NPs 64

3.3.1 Influence of Organic Matter on Sorption 64

3.3.2 Influence of TiO2 NP Surface Area on Sorption 64

3.3.3 Use of Bioavailability to Inform on Sorption of Organic Compounds on TiO2 NPs 66

3.4 Conclusions 72

References 73

4 Behavior, Fate, and Toxicity of Engineered Nanoparticles in Estuarine and Coastal Environments 79
Daniel M. Lyons and Petra Buric

4.1 Introduction 79

4.2 Types of Nanoparticles: Sources/Products/Release Routes 80

4.3 Behavior of Nanoparticles in the Water Column 82

4.4 Biota, Trophic Transfer, Toxicity, and Mechanisms 84

4.5 Measurement Issues and Regulatory Environment 94

4.6 Modeling 94

4.7 Knowledge Gaps and Research Prospects 95

References 96

5 Interactive Effects of Nanomaterials with Other Contaminants on Aquatic Organisms: nTiO2 as a Case Study 101
Laura Canesi, Camilla Della Torre, Teresa Balbi, and Ilaria Corsi

5.1 Introduction 101

5.2 Interactive Effects of NPs with Other Contaminants in Aquatic Organisms: nTiO2 as a Case Study 104

5.3 Interactions Between nTiO2 and Other Contaminants in Marine Invertebrates: The Example of the Bivalve Mytilus 106

5.3.1 Effects of nTiO2 and Cd²+ 106

5.3.2 Effects of nTiO2 and TCDD 109

5.4 Interactions Between nTiO2 and Other Contaminants in Marine Fish: The Example of the European Sea Bass (Dicentrarchus labrax) 111

5.5 Interactive Effects of NPs with Other Contaminants in Marine Species: Importance of Exposure Media 114

5.6 Concluding Remarks 115

Acknowledgments 115

References 115

6 Soil Nano-ecotoxicology: What Have We Learned from Standard Tests and What May We Be Missing? 121
David J. Spurgeon, Elma Lahive, Carolin Schultz, and Claus Svendsen

6.1 Introduction 121

6.2 Development of Standard Test Methods and Their Application to Nanomaterials 122

6.3 From Soil Ecotoxicological Tests to Risk Assessment 127

6.4 Looking Beyond Standa