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The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years. This book represents a culmination of knowledge gained from human and experimental animal studies over the past decade. It examines the effect of selected pollutants on the upper airways of humans and animals and epidemiologic findings from populations exposed occupationally or environmentally. Chapters are organized into clear sections on structure and function, dosimetry…mehr

Produktbeschreibung
The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years. This book represents a culmination of knowledge gained from human and experimental animal studies over the past decade. It examines the effect of selected pollutants on the upper airways of humans and animals and epidemiologic findings from populations exposed occupationally or environmentally. Chapters are organized into clear sections on structure and function, dosimetry and toxicokinetics, functional and pathologic responses and their measurement, responses to specific agents, risk assessment, and special topics.
Autorenporträt
John B. Morris is Professor and Head of Pharmaceutical Sciences and Assistant Dean for Research at the University of Connecticut. He received his Ph.D. in Toxicology at the University of Rochester in 1979 and carried out a Postdoctoral fellowship in Inhalation Toxicology at New York University. In 1981 he joined the faculty at the University of Connecticut. Dr Morris has authored over 70 peer-review articles and book chapters. He is currently on the editorial board of Inhalation Toxicology. Dennis J. Shusterman is Professor of Clinical Medicine, Emeritus at the University of California, San Francisco (UCSF). He received his M.D. from University of California, Davis in 1978, and M.P.H. from University of California, Berkley in 1982. He currently serves as a Section Chief within the Occupational Health Branch of the California Department of Public Health, and is an attending physician in the Occupational and Environmental Medicine Clinic at UCSF. He is the author of over 70 peer-reviewed publications in the field of inhalation toxicology and occupational and environmental medicine.