Written by the international community's leading experts, Trace Elements in Laboratory Rodents describes the best and most current methods to provide deficient or supplemental trace elements to laboratory animals, as well as how to assay them
Written by the international community's leading experts, Trace Elements in Laboratory Rodents describes the best and most current methods to provide deficient or supplemental trace elements to laboratory animals, as well as how to assay them
General Overview: AIN-93 Purified Diets for the Study of Trace Elements Metabolism in Rodents. Basic Tissue Preparation for Electron Microscopy Assessment of Rodents. Iron: Dietary Iron: Deficiency or Excess. The Use of Iron-Dextran to Produce Iron Overload in Rodents. Extraction and Analysis of Iron Species in Diet and Gut. Manganese: Manganese Deficiency and Excess in Rodents. Manganese Uptake in Tissues In Vitro: Tissue Slices as Models. Selenium: Selenium Diets: Deficiency and Excess. Selenium in Tissue Culture. Copper: Copper Deficient and Excess Diets: Theoretical Considerations and Preparations. Copper in Tissue Culture. Zinc: Zinc Diets: Deficiency and Excess. Zinc Radiotracer in the Study of the Mechanisms of Zinc Homeostasis. Other Trace Elements: Dietary Boron Deficiency and Supplementation. Measurements of Boron in Rodent Diets and Tissues. Methods for Studying Dietary Lead and its Toxicity in Rodents. Methods in Chromium Dietary Supplementation and Deficiency. Isolation and In Vitro Analysis of Biologically Active Chromium. Calcium Bioavailability Using a Rat Model. Vanadium Quantitation, Essentiality, and Pharmacologic and Toxicological Studies in Rodents. Nickel-Low Diet Formulation and Tissue Nickel Measurement. Index.Summary of the Contents: General Overview 1. AIN-93 Purified Diets for the Study of Trace Elements Metabolism in Rodents 2. Basic Tissue Preparation for Electron Microscopy Assessment of Rodents Iron 3. Dietary Iron: Deficiency or Excess 4. The Use of Iron-Dextran to Produce Iron Overload in Rodents 5. Extractin and Analysis of Iron Species in Diet and Gut Manganese 6. Manganese Deficiency and Excess in Rodents 7. Manganese Uptake in Tissues In Vitro: Tissue Slices as Models Selenium 8. Selenium Diets: Deficiency and Excess 9. Selenium in Tissue Culture Copper 10. Copper-Deficient and Excess Diets: Theoretical Considerations and Preparations 11. Copper in Tissue Culture Zinc 12. Zinc Diets: Deficiency and Excess 13. Zinc Radiotracer in the Study of the Mechanisms of Zinc Homeostasis Other Trace Elements 14. Dietary Boron Deficiency and Supplementation 15. Measurements of Boron in Rodent Diets and Tissues 16. Methods for Studying Dietary Lead and Its Toxicity in Rodents 17. Methods in Chromium Dietary Supplementation 18. Isolation and In Vitro Analysis of Biologically Active Chromium 19. Calcium Biovalability Using A Rat Model 20. Vanadium: Quantitation, Essentiality, and Pharmacologic and Toxicologic Studies in Rodents 21. Nickel-Low Diet Formulation and Tissue Nickel Measurement
General Overview: AIN-93 Purified Diets for the Study of Trace Elements Metabolism in Rodents. Basic Tissue Preparation for Electron Microscopy Assessment of Rodents. Iron: Dietary Iron: Deficiency or Excess. The Use of Iron-Dextran to Produce Iron Overload in Rodents. Extraction and Analysis of Iron Species in Diet and Gut. Manganese: Manganese Deficiency and Excess in Rodents. Manganese Uptake in Tissues In Vitro: Tissue Slices as Models. Selenium: Selenium Diets: Deficiency and Excess. Selenium in Tissue Culture. Copper: Copper Deficient and Excess Diets: Theoretical Considerations and Preparations. Copper in Tissue Culture. Zinc: Zinc Diets: Deficiency and Excess. Zinc Radiotracer in the Study of the Mechanisms of Zinc Homeostasis. Other Trace Elements: Dietary Boron Deficiency and Supplementation. Measurements of Boron in Rodent Diets and Tissues. Methods for Studying Dietary Lead and its Toxicity in Rodents. Methods in Chromium Dietary Supplementation and Deficiency. Isolation and In Vitro Analysis of Biologically Active Chromium. Calcium Bioavailability Using a Rat Model. Vanadium Quantitation, Essentiality, and Pharmacologic and Toxicological Studies in Rodents. Nickel-Low Diet Formulation and Tissue Nickel Measurement. Index.Summary of the Contents: General Overview 1. AIN-93 Purified Diets for the Study of Trace Elements Metabolism in Rodents 2. Basic Tissue Preparation for Electron Microscopy Assessment of Rodents Iron 3. Dietary Iron: Deficiency or Excess 4. The Use of Iron-Dextran to Produce Iron Overload in Rodents 5. Extractin and Analysis of Iron Species in Diet and Gut Manganese 6. Manganese Deficiency and Excess in Rodents 7. Manganese Uptake in Tissues In Vitro: Tissue Slices as Models Selenium 8. Selenium Diets: Deficiency and Excess 9. Selenium in Tissue Culture Copper 10. Copper-Deficient and Excess Diets: Theoretical Considerations and Preparations 11. Copper in Tissue Culture Zinc 12. Zinc Diets: Deficiency and Excess 13. Zinc Radiotracer in the Study of the Mechanisms of Zinc Homeostasis Other Trace Elements 14. Dietary Boron Deficiency and Supplementation 15. Measurements of Boron in Rodent Diets and Tissues 16. Methods for Studying Dietary Lead and Its Toxicity in Rodents 17. Methods in Chromium Dietary Supplementation 18. Isolation and In Vitro Analysis of Biologically Active Chromium 19. Calcium Biovalability Using A Rat Model 20. Vanadium: Quantitation, Essentiality, and Pharmacologic and Toxicologic Studies in Rodents 21. Nickel-Low Diet Formulation and Tissue Nickel Measurement
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"...a 'how-to-do book' that weould be a welcome addition in any nutritional or toxicological scientist's lib rary....Ronald Watson has done a marvelous job in assembling 21 detailed chapters into a comprehensive reference....a great text for those who need a resource that focuses on the details. This book will serve as a key reference resource for the researcher, nutritionalist, toxicologist, and veterinary or animal care person. In addition, it could serve well as a supplemental book for a graduate course on nutrition and trace elements." -Environmental Nutrition International "Designed for the researcher with a focus on laboratory and field nutritional research." - Ira Wolinsky, Series Editor
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