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The basic fundamental of Trans Dermal Drug delivery system is to deliver the right amount of dosage, at the right time to the right target. Thus increased patient compliance with Avoidance of the first pass metabolism and Controlled and consistent administration of the drug. Targeting the skin for drug delivery Via can be possible by delivering the drug moiety through the surface of the skin, Through the skin (subcutaneous) and Direct delivery of drug molecule, into the systemic circulation. Drug penetration pathway Sweat ducts Hair follicles Sebaceous glands helps drug moiety to transfer…mehr

Produktbeschreibung
The basic fundamental of Trans Dermal Drug delivery system is to deliver the right amount of dosage, at the right time to the right target. Thus increased patient compliance with Avoidance of the first pass metabolism and Controlled and consistent administration of the drug. Targeting the skin for drug delivery Via can be possible by delivering the drug moiety through the surface of the skin, Through the skin (subcutaneous) and Direct delivery of drug molecule, into the systemic circulation. Drug penetration pathway Sweat ducts Hair follicles Sebaceous glands helps drug moiety to transfer directly across the stratum Corneum. Vesicular Approach for Modulation of Transdermal Penetration Colloidal particles formed as a concentric bio molecular layer that are capable of encapsulating drugs and are composed of the lipids, that are similar to the lipids present in the stratum corneum. Ethosomes Elastic vesicles, primarily composed of phospholipids Contains a high concentrations of Ethanol (up to 20-50 %). Average diameter, ranges from nanometers to microns. They can be either Unilamellar or Multilamellar. Ethosomes significantly enhances the drug delivery across the skin.
Autorenporträt
Ghai, IshanAbout the author: Ishan Ghai currently working as a research director in m/s Rsg Biogen, Delhi, India. He has authored various review scripts and held position of associate creative head in Savig healthcare and a member of Delhi Pharmacy Council. He Obtain B.Pharmacy degree from Jamia Hamdard University and m.pharmacy from PGIMS Harayana India