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Transfusion-related acute pulmonary edema (TRALI) is a transfusion-related incident whose etiology and pathophysiology are still debated, suggesting immunological or non-immunological mechanisms, following leukocyte activation by biological response modifiers (BRMs) supplied by transfused labile blood products (LBP).Using 4 cases of TRALI reported to the haemovigilance unit of the Sfax CRTS, we discuss epidemiology, pathophysiology, positive and differential diagnosis, management and primary and secondary prevention.

Produktbeschreibung
Transfusion-related acute pulmonary edema (TRALI) is a transfusion-related incident whose etiology and pathophysiology are still debated, suggesting immunological or non-immunological mechanisms, following leukocyte activation by biological response modifiers (BRMs) supplied by transfused labile blood products (LBP).Using 4 cases of TRALI reported to the haemovigilance unit of the Sfax CRTS, we discuss epidemiology, pathophysiology, positive and differential diagnosis, management and primary and secondary prevention.
Autorenporträt
Dr. Nour Louati, MD-PhD, Associate Professor of Medicine, Hämatobiologie, Flow Cytometry Unit, Laboratory of Hemobiology, Sfax Regional Blood Transfusion Centre, University of Sfax, Faculty of Medicine of Sfax, Tunesia.