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Transmembrane Transporters
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This comprehensive text provides readers with a state-of-the-art molecule update on transmembrane transporters, focusing on the methodological approaches currently employed to better understand how transporters work and how they can be applied in cutting-edge therapies. This book is organized by experimental approaches, including chapters devoted to: informatics, expression strategies, high-throughput screening, molecular genetics, structural analyses (NMR, crystallization, freeze fracture, and chimeras), and functional analyses (imaging, electrophysiology, and microdialysis).
A must-have far-reaching text that provides readers with a state-of-the-art molecule update on transmembrane transporters, focusing on the methodological approaches currently employed to better understand how transporters work and how they can be used in cutting edge therapies. Each chapter begins with an overview of the importnat biological questions presently being considered in their field, then presents scientific approaches to address these questions. In explaining approaches, the authors cover bench-top protocols, conceptual frameworks, data obtained, and pitfalls common to the techniques.
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