Amoebiasis is main zoonotic disease which also infect other animal such as non human primates, dogs, cat,bovine and reptiles(snakes, lizards and tortoises) but the studies on those hosts are not enough.the disease transmitted through fecal oral route and contamination of food by cysts. the disease highly prevalent in developing countries with low hygienic practice. The causative agent of the dIsease are E. histolytica, E.polick, E. bovis and others.