Sophia Dean

Transplantation of Fetal Pig Islet-like Cell Clusters as Therapy for Diabetes

Fetal Pig Insulin Cells as Therapy for Diabetes

• Broschiertes Buch

Produktbeschreibung

Type 1 diabetes is an autoimmune disease in which the insulin-producing cells of the pancreas are destroyed. Complications that arise from type 1 diabetes include blindness, kidney failure and nerve damage. Current treatment is with daily insulin injections, although some may be eligible for a pancreas or islet transplant. However, this is usually reserve for those with end-stage kidney failure. Furthermore, there are not enough donors to meet this demand should every diabetic receive a pancreas or islet transplant. It is for this reason that alternative sources of insulin-producing cells must be considered as another form of treatment.In this book, the transplantation of insulin cells from the fetal pig pancreas is examined as an alternative therapy, with the use of the outbred pig as an animal model for type 1 diabetes. A historical perspective of diabetes is also discussed as well as the different types of anti-rejection drugs used and the mechanisms of graft rejection. Finally, the possibility of eliminating the need for anti-rejection drugs through the means of encapsulation, is explored.

Produktdetails

• Verlag: VDM Verlag Dr. Müller / VDM Verlag Dr. Müller e.K.
• Seitenzahl: 384
• Englisch
• Abmessung: 220mm x 150mm x 23mm
• Gewicht: 588g
• ISBN-13: 9783836483582
• ISBN-10: 3836483580
• Artikelnr.: 23606554

Autorenporträt

Dean, Sophia§Sophia K. Dean, PhD: Having an agricultural science background (Sydney University), she went on to do a PhD (University of New South Wales) studying whether fetal pig insulin cells can be used as an alternative therapy for type 1 diabetes. As a post-doctoral fellow, she is currently working on converting skin-derived adult stem cells into neurons.